Aggregation and Contextualization of Murine Investigations Improves Discovery of Significant Human Atherosclerotic Cardiovascular Disease Associations

Circulation. 2024 Mar 26;149(13):1056-1058. doi: 10.1161/CIRCULATIONAHA.123.067510. Epub 2024 Mar 25.
No abstract available

Keywords: ApoE; atherosclerosis; disease models, animal; human genetics; mice, knockout; receptors, low density lipoprotein; systems biology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apolipoproteins E
  • Atherosclerosis* / genetics
  • Cardiovascular Diseases* / therapy
  • Disease Models, Animal
  • Humans
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Plaque, Atherosclerotic*

Substances

  • Apolipoproteins E