Chronic Coronary Disease in Older Adults

Alexander P Ambrosini; Emily S Fishman; Abdulla A Damluji; Michael G Nanna

doi:10.1016/j.mcna.2023.12.004

Chronic Coronary Disease in Older Adults

Med Clin North Am. 2024 May;108(3):581-594. doi: 10.1016/j.mcna.2023.12.004. Epub 2024 Jan 4.

Authors

Alexander P Ambrosini¹, Emily S Fishman¹, Abdulla A Damluji², Michael G Nanna³

Affiliations

¹ Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
² Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA, USA; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
³ Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address: michael.nanna@yale.edu.

PMID: 38548465
PMCID: PMC11040602 (available on 2025-05-01)
DOI: 10.1016/j.mcna.2023.12.004

Abstract

The number of older adults age ≥75 with chronic coronary disease (CCD) continues to rise. CCD is a major contributor to morbidity, mortality, and disability in older adults. Older adults are underrepresented in randomized controlled trials of CCD, which limits generalizability to older adults living with multiple chronic conditions and geriatric syndromes. This review discusses the presentation of CCD in older adults, reviews the guideline-directed medical and invasive therapies, and recommends a patient-centric approach to making treatment decisions.

Keywords: Aging; Coronary artery disease; Geriatrics; Older adults; Revascularization.

Publication types

Review

MeSH terms

Aged
Coronary Disease* / diagnosis
Coronary Disease* / therapy
Heart Diseases*
Humans
Morbidity
Randomized Controlled Trials as Topic

Abstract

Publication types

MeSH terms

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