EQ-5D-5L population norms for China derived from a national health survey

Danlin Li; Zitong Wang; Xinyi Nie; Nan Luo; Yibo Wu; Chenwei Pan; Pei Wang

doi:10.1016/j.jval.2024.04.014

EQ-5D-5L population norms for China derived from a national health survey

Value Health. 2024 Apr 25:S1098-3015(24)02346-5. doi: 10.1016/j.jval.2024.04.014. Online ahead of print.

Authors

Danlin Li¹, Zitong Wang², Xinyi Nie¹, Nan Luo³, Yibo Wu⁴, Chenwei Pan¹, Pei Wang⁵

Affiliations

¹ School of Public Health, Medical College of Soochow University, China, Jiangsu, Suzhou.
² School of Public Health, Fudan University, China, Shanghai; Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, China, Shanghai.
³ National University of Singapore, Singapore, Singapore.
⁴ School of Public Health, Peking University, China, Beijing. Electronic address: bjmuwuyibo@outlook.com.
⁵ School of Public Health, Fudan University, China, Shanghai; Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, China, Shanghai. Electronic address: wang_p@fudan.edu.cn.

PMID: 38677363
DOI: 10.1016/j.jval.2024.04.014

Abstract

Objectives: To develop the EQ-5D-5L (5L) population norms for China; and to assess the relationship between various factors and 5L data.

Methods: The study used data derived from the Psychology and Behavior Investigation of Chinese Residents, a national sample survey of 21,909 representative participants aged 12 years and above. Participants' health-related quality of life (HRQoL) was measured by the 5L. Their socioeconomic characteristics, behavioral factors, and health conditions were also obtained from the survey. Norm scores were generated and compared for different socioeconomic variables. Multiple linear and logistic regressions were used to assess the relationships of the three kinds of variables with the 5L utility, visual analogue scale (VAS) scores and 5L health problems.

Results: The mean (SD) age of participants was 39.4 (18.9) years, and 50.0% of the participants were female. The mean (SD) utility and VAS scores were 0.940 (0.138) and 73.4 (21.6), respectively. Participants reported considerably more problems in anxiety/depression (26.2%) and pain/discomfort (22.2%) dimensions. The gender difference in HRQoL is attenuated. The participants older than 75 years suffered from a sharp decline in HRQoL; the participants in Shanghai and Tibet provinces reported lower utility and VAS scores and more health problems. Those who were younger, with better socioeconomic status and healthier lifestyles, and without diseases tended to report higher utility and VAS scores and fewer health problems.

Conclusions: The study derived the 5L population norms for China based on a representative population sample.

Keywords: Chinese population norms; EQ-5D-5L; Health-related quality of life measurement.