Urethral-sparing laparoscopic simple prostatectomy for the treatment of benign prostatic hyperplasia with asymptomatic urethral stricture after urethral stricture surgery

BMC Urol. 2024 Apr 30;24(1):99. doi: 10.1186/s12894-024-01487-8.

Abstract

Objective: To evaluate the efficacy of urethral-sparing laparoscopic simple prostatectomy (US-LSP) for the treatment of large-volume (>80 ml) benign prostatic hyperplasia (BPH) with asymptomatic urethral stricture (urethral lumen > 16 Fr) after urethral stricture surgery.

Methods: We retrospectively analyzed clinical data of 39 large-volume BPH patients with asymptomatic urethral stricture after urethral stricture surgery who underwent US-LSP from January 2016 to October 2021. Postoperative follow-ups were scheduled at 1, 3, and 6 months.

Results: All patients affected by significant BPH-related lower urinary tract symptoms (LUTS) including 22 cases with asymptomatic anterior urethral stricture and 17 cases with asymptomatic posterior urethral stricture. Median operative time was 118 min (interquartile range [IQR]100-145). Median estimated blood loss was 224 ml (IQR: 190-255). 33 patients(84.6%) avoided continuous bladder irrigation. Postoperative complications occurred in 5 patients (12.8%), including 4 cases with Clavien-Dindo grade 1 and grade 2 and 1 case with grade 3a. During follow-up, US-LSP presented statistically significant improvements in LUTS compared to baseline (P < 0.05). A total of 25 patients had normal ejaculation preoperatively and 3 patients (12%) complained retrograde ejaculation postoperatively. Two patients (5.1%) reported stress urinary incontinence (SUI) and no patient reported aggravated urethral stricture during follow-up.

Conclusions: US-LSP was safe and effective in treating large-volume BPH with asymptomatic urethral stricture after urethral stricture surgery. Meanwhile, US-LSP could reduce the risk of SUI in patients with asymptomatic posterior urethral stricture and maintain ejaculatory function in a high percentage of patients.

Keywords: Begin prostatic hyperplasia; Laparoscopy Prostatectomy; Urethral stricture.

MeSH terms

  • Aged
  • Asymptomatic Diseases
  • Humans
  • Laparoscopy*
  • Male
  • Middle Aged
  • Organ Sparing Treatments / methods
  • Postoperative Complications / etiology
  • Prostatectomy* / adverse effects
  • Prostatectomy* / methods
  • Prostatic Hyperplasia* / complications
  • Prostatic Hyperplasia* / surgery
  • Retrospective Studies
  • Treatment Outcome
  • Urethra / surgery
  • Urethral Stricture* / etiology
  • Urethral Stricture* / surgery