Addressing challenges for repairing adult spinal cord with insights from neonates

Mickey E Abraham; Joel Martin; Joseph D Ciacci

doi:10.1016/j.stem.2024.04.008

Addressing challenges for repairing adult spinal cord with insights from neonates

Cell Stem Cell. 2024 May 2;31(5):585-586. doi: 10.1016/j.stem.2024.04.008.

Authors

Mickey E Abraham¹, Joel Martin², Joseph D Ciacci³

Affiliations

¹ Department of Neurological Surgery, University of California, San Diego, La Jolla, CA 92037, USA. Electronic address: mabraham@health.ucsd.edu.
² Department of Neurological Surgery, Orlando Health, Orlando, FL, USA.
³ Department of Neurological Surgery, University of California, San Diego, La Jolla, CA 92037, USA.

PMID: 38701752
DOI: 10.1016/j.stem.2024.04.008

Abstract

Stem cell therapy has emerged as a promising area of scientific investigation, sparking considerable interest, especially in spinal cord injury (SCI). Sun et al.¹ discover that the extracellular matrix (ECM) from the neonatal spinal cord transmits biochemical signals to endogenous axons, thus promoting axonal regeneration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Animals
Extracellular Matrix / metabolism
Humans
Infant, Newborn
Nerve Regeneration
Spinal Cord Injuries* / therapy
Spinal Cord*