Downregulation of protein S in patients with severe COVID-19 augments the prothrombotic state

Thromb Res. 2024 Jun:238:129-131. doi: 10.1016/j.thromres.2024.04.021. Epub 2024 May 1.

Authors

Devin Melancon¹, Tina Nguyen¹, Verima Pereira¹, Jarrod Harman¹, Sabyasachi Chatterjee¹, Arnold H Zea¹, Samarpan Majumder¹, Rinku Majumder²

Affiliations

¹ Louisiana State University Health Sciences Center, Department of Interdisciplinary Oncology, 533 Bolivar Street, New Orleans, LA 70112, United States of America.
² Louisiana State University Health Sciences Center, Department of Interdisciplinary Oncology, 533 Bolivar Street, New Orleans, LA 70112, United States of America. Electronic address: rmajum@lsuhsc.edu.

PMID: 38703586
DOI: 10.1016/j.thromres.2024.04.021

No abstract available

Keywords: COVID-19; Coagulation; Hypoxia; Protein S; Thrombomodulin.

Publication types

Letter

MeSH terms

Aged
COVID-19* / blood
COVID-19* / complications
COVID-19* / virology
Down-Regulation*
Female
Humans
Male
Middle Aged
Protein S* / metabolism
SARS-CoV-2*
Thrombosis* / blood

Substances

PROS1 protein, human