Transcatheter-Based Interventions for Tetralogy of Fallot Across All Age Groups

Eduardo Flores-Umanzor; Bandar Alshehri; Rajesh Keshvara; William Wilson; Mark Osten; Lee Benson; Lusine Abrahamyan; Eric Horlick

doi:10.1016/j.jcin.2024.02.009

Transcatheter-Based Interventions for Tetralogy of Fallot Across All Age Groups

JACC Cardiovasc Interv. 2024 May 13;17(9):1079-1090. doi: 10.1016/j.jcin.2024.02.009.

Authors

Eduardo Flores-Umanzor¹, Bandar Alshehri², Rajesh Keshvara², William Wilson³, Mark Osten², Lee Benson⁴, Lusine Abrahamyan⁵, Eric Horlick⁶

Affiliations

¹ Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada; Cardiology Department, Cardiovascular Institute, Hospital Clínic, University of Barcelona, Barcelona, Spain.
² Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
³ Royal Melbourne Hospital Cardiology, Parkville, Victoria, Australia.
⁴ Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada; The Labatt Family Heart Centre, Division of Cardiology, The Hospital for Sick Children, The Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
⁵ Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada; Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada.
⁶ Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada. Electronic address: Eric.Horlick@uhn.ca.

PMID: 38749587
DOI: 10.1016/j.jcin.2024.02.009

Abstract

Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease. Palliative procedures, either surgical or transcatheter, aim to improve oxygen saturation, affording definitive procedures at a later stage. Transcatheter interventions have been used before and after surgical palliative or definitive repair in children and adults. This review aims to provide an overview of the different catheter-based interventions for TOF across all age groups, with an emphasis on palliative interventions, such as patent arterial duct stenting, right ventricular outflow tract stenting, or balloon pulmonary valvuloplasty in infants and children and transcatheter pulmonary valve replacement in adults with repaired TOF, including the available options for a large, dilated native right ventricular outflow tract.

Keywords: congenital heart disease; tetralogy of Fallot; transcatheter interventions.

Publication types

Review

MeSH terms

Adolescent
Adult
Age Factors
Balloon Valvuloplasty*
Cardiac Catheterization* / adverse effects
Cardiac Catheterization* / instrumentation
Cardiac Surgical Procedures / adverse effects
Child
Child, Preschool
Female
Heart Valve Prosthesis Implantation* / adverse effects
Heart Valve Prosthesis Implantation* / instrumentation
Hemodynamics
Humans
Infant
Infant, Newborn
Male
Middle Aged
Palliative Care*
Pulmonary Valve / diagnostic imaging
Pulmonary Valve / physiopathology
Pulmonary Valve / surgery
Recovery of Function
Risk Factors
Stents*
Tetralogy of Fallot* / diagnostic imaging
Tetralogy of Fallot* / physiopathology
Tetralogy of Fallot* / surgery
Treatment Outcome
Young Adult