Dietary anti-inflammatory and anti-bacterial medicinal plants and its compounds in bovine mastitis associated impact on human life

Vinod Kumar Nelson; Mohana Vamsi Nuli; Saijyothi Ausali; Saurabh Gupta; Vaishnavi Sanga; Richa Mishra; Pavan Kumar Jaini; Sudha Divya Madhuri Kallam; Hari Hara Sudhan; Vinyas Mayasa; Mosleh Mohammad Abomughaid; Abdulmajeed G Almutary; Chitikela P Pullaiah; Raghavendra Mitta; Niraj Kumar Jha

doi:10.1016/j.micpath.2024.106687

Dietary anti-inflammatory and anti-bacterial medicinal plants and its compounds in bovine mastitis associated impact on human life

Microb Pathog. 2024 May 13:192:106687. doi: 10.1016/j.micpath.2024.106687. Online ahead of print.

Authors

Vinod Kumar Nelson¹, Mohana Vamsi Nuli², Saijyothi Ausali³, Saurabh Gupta⁴, Vaishnavi Sanga², Richa Mishra⁵, Pavan Kumar Jaini⁶, Sudha Divya Madhuri Kallam⁷, Hari Hara Sudhan², Vinyas Mayasa⁸, Mosleh Mohammad Abomughaid⁹, Abdulmajeed G Almutary¹⁰, Chitikela P Pullaiah¹¹, Raghavendra Mitta¹², Niraj Kumar Jha¹³

Affiliations

¹ Center for global health research, saveetha medical college, saveetha institute of medical and technical sciences, India. Electronic address: Vinod.kumar457@gmail.com.
² Raghavendra Institute of Pharmaceutical Education and Research, Anantapur, India.
³ College of Pharmacy, MNR higher education and research academy campus, MNR Nagar, Sangareddy, 502294, India.
⁴ Department of Biotechnology, GLA University, Mathura, Uttar Pradesh, India.
⁵ Department of Computer Engineering, Faculty of Engineering and Technology, Parul University, Vadodara, 391760, Gujrat, India.
⁶ Department of Pharmaceutics, Raffles University, Neemrana, Rajasthan, India.
⁷ Department of Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research (Deemed to be University), Guntur, Vadlamudi, Andhra Pradesh, 522213, India.
⁸ GITAM School of Pharmacy, GITAM University Hyderabad Campus, Rudraram, India.
⁹ Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha, 61922, Saudi Arabia.
¹⁰ Department of Biomedical Sciences, College of Health Sciences, Abu Dhabi University, Abu Dhabi, P.O. Box, 59911, United Arab Emirates.
¹¹ Department of Chemistry, Siddha Central Research Institute, Chennai, Tamil Nadu, 60016, India.
¹² Department of Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research (Deemed to be University), Vadlamudi, Guntur, 522213, Andhra Pradesh, India.
¹³ Department of Biotechnology, Sharda School of Engineering & Technology (SSET), Sharda University, Greater Noida, India; School of Bioengineering & Biosciences, Lovely Professional University, Phagwara, 144411, India; Department of Biotechnology, School of Applied & Life Sciences (SALS), Uttaranchal University, Dehradun, 248007, India. Electronic address: nirajkumarjha2011@gmail.com.

PMID: 38750773
DOI: 10.1016/j.micpath.2024.106687

Abstract

Bovine mastitis (BM) is the most common bacterial mediated inflammatory disease in the dairy cattle that causes huge economic loss to the dairy industry due to decreased milk quality and quantity. Milk is the essential food in the human diet, and rich in crucial nutrients that helps in lowering the risk of diseases like hypertension, cardiovascular diseases and type 2 diabetes. The main causative agents of the disease include various gram negative, and positive bacteria, along with other risk factors such as udder shape, age, genetic, and environmental factors also contributes much for the disease. Currently, antibiotics, immunotherapy, probiotics, dry cow, and lactation therapy are commonly recommended for BM. However, these treatments can only decrease the rise of new cases but can't eliminate the causative agents, and they also exhibit several limitations. Hence, there is an urgent need of a potential source that can generate a typical and ideal treatment to overcome the limitations and eliminate the pathogens. Among the various sources, medicinal plants and its derived products always play a significant role in drug discovery against several diseases. In addition, they are also known for its low toxicity and minimum resistance features. Therefore, plants and its compounds that possess anti-inflammatory and anti-bacterial properties can serve better in bovine mastitis. In addition, the plants that are serving as a food source and possessing pharmacological properties can act even better in bovine mastitis. Hence, in this evidence-based study, we particularly review the dietary medicinal plants and derived products that are proven for anti-inflammatory and anti-bacterial effects. Moreover, the role of each dietary plant and its compounds along with possible role in the management of bovine mastitis are delineated. In this way, this article serves as a standalone source for the researchers working in this area to help in the management of BM.

Keywords: Antibiotic resistance; Bacteria; Cattle; Feed; Inflammation; Mastitis; Phytocompounds; Plant extract.

Publication types

Review