Towards antiviral oligopeptide vaccines

Microbiol Sci. 1984 Jun;1(3):55-8.

Abstract

Synthetic peptides, representing part of the viral proteins, can be used as effective vaccines. Using this approach, it is even possible to raise neutralizing antibodies against domains which are not immunogenic in the native protein. Further research is needed to develop the adequate protein carriers and adjuvants. Anticipation of the antigenic drift of viruses is also essential to ensure the efficacy of vaccines.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antibodies, Viral / biosynthesis
  • Antigenic Variation
  • Antigens, Viral
  • Epitopes
  • Humans
  • Oligopeptides / immunology*
  • Vaccines, Synthetic / isolation & purification
  • Viral Proteins / immunology
  • Viral Vaccines / isolation & purification*
  • Virus Diseases / prevention & control

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Epitopes
  • Oligopeptides
  • Vaccines, Synthetic
  • Viral Proteins
  • Viral Vaccines