Abstract
Sesquiterpene lactones are a large, diverse group of chemicals found in several plant families that cause allergic contact dermatitis. The biological, botanical, allergenic, and structural significance of sesquiterpene lactones is explored as well as the clinical characteristics of cutaneous reactions. The association with UV-light sensitivity and proposed mechanisms for this relationship as well as new developments in patch test methods and treatment are reviewed.
MeSH terms
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Adult
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Age Distribution
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Allergens*
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Dermatitis, Allergic Contact / drug therapy
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Dermatitis, Allergic Contact / epidemiology
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Dermatitis, Allergic Contact / etiology*
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Dermatitis, Photoallergic / diagnosis*
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Dermatitis, Photoallergic / drug therapy
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Dermatitis, Photoallergic / epidemiology
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Female
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Humans
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Incidence
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Lactones / adverse effects
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Male
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Middle Aged
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Patch Tests
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Plant Extracts* / adverse effects
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Sesquiterpenes / adverse effects*
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Sesquiterpenes / chemistry
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Sex Distribution
Substances
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Allergens
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Lactones
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Plant Extracts
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Sesquiterpenes