Fesik SW - Search Results

1

Novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 2. Mechanism of inhibition and structure-based improvement of pharmaceutical properties.

Liu G, Huth JR, Olejniczak ET, Mendoza R, DeVries P, Leitza S, Reilly EB, Okasinski GF, Fesik SW, von Geldern TW. Liu G, et al. Among authors: fesik sw. J Med Chem. 2001 Apr 12;44(8):1202-10. doi: 10.1021/jm000503f. J Med Chem. 2001. PMID: 11312920

2

Side chain and backbone assignments in isotopically labeled proteins from two heteronuclear triple resonance experiments.

Logan TM, Olejniczak ET, Xu RX, Fesik SW. Logan TM, et al. Among authors: fesik sw. FEBS Lett. 1992 Dec 21;314(3):413-8. doi: 10.1016/0014-5793(92)81517-p. FEBS Lett. 1992. PMID: 1281793 Free article.

3

A 4D HCCH-TOCSY experiment for assigning the side chain 1H and 13C resonances of proteins.

Olejniczak ET, Xu RX, Fesik SW. Olejniczak ET, et al. Among authors: fesik sw. J Biomol NMR. 1992 Nov;2(6):655-9. doi: 10.1007/BF02192854. J Biomol NMR. 1992. PMID: 1283353

4

Stereospecific assignments and chi 1 rotamers for FKBP when bound to ascomycin from 3JH alpha,H beta and 3HN,H beta coupling constants.

Xu RX, Olejniczak ET, Fesik SW. Xu RX, et al. Among authors: fesik sw. FEBS Lett. 1992 Jun 29;305(2):137-43. doi: 10.1016/0014-5793(92)80881-g. FEBS Lett. 1992. PMID: 1377648 Free article.

5

NMR studies of an FK-506 analog, [U-13C]ascomycin, bound to FK-506-binding protein.

Petros AM, Gemmecker G, Neri P, Olejniczak ET, Nettesheim D, Xu RX, Gubbins EG, Smith H, Fesik SW. Petros AM, et al. Among authors: fesik sw. J Med Chem. 1992 Jun 26;35(13):2467-73. doi: 10.1021/jm00091a015. J Med Chem. 1992. PMID: 1377749

6

NMR studies of molecular complexes as a tool in drug design.

Fesik SW. Fesik SW. J Med Chem. 1991 Oct;34(10):2937-45. doi: 10.1021/jm00114a001. J Med Chem. 1991. PMID: 1920348 Review. No abstract available.

7

NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding.

Fesik SW, Gampe RT Jr, Eaton HL, Gemmecker G, Olejniczak ET, Neri P, Holzman TF, Egan DA, Edalji R, Simmer R, et al. Fesik SW, et al. Biochemistry. 1991 Jul 2;30(26):6574-83. doi: 10.1021/bi00240a030. Biochemistry. 1991. PMID: 2054356

8

NMR methods for determining the structures of enzyme/inhibitor complexes as an aid in drug design.

Fesik SW, Zuiderweg ER, Olejniczak ET, Gampe RT Jr. Fesik SW, et al. Biochem Pharmacol. 1990 Jul 1;40(1):161-7. doi: 10.1016/0006-2952(90)90191-m. Biochem Pharmacol. 1990. PMID: 2115336 Review.

9

NMR study of the solution conformation of rat atrial natriuretic factor 7-23 in sodium dodecyl sulfate micelles.

Olejniczak ET, Gampe RT Jr, Rockway TW, Fesik SW. Olejniczak ET, et al. Among authors: fesik sw. Biochemistry. 1988 Sep 6;27(18):7124-31. doi: 10.1021/bi00418a069. Biochemistry. 1988. PMID: 2973811

10

Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.

Sham HL, Bolis G, Stein HH, Fesik SW, Marcotte PA, Plattner JJ, Rempel CA, Greer J. Sham HL, et al. Among authors: fesik sw. J Med Chem. 1988 Feb;31(2):284-95. doi: 10.1021/jm00397a003. J Med Chem. 1988. PMID: 3276890

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