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Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals.
Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Bethony J, et al. Among authors: lustigman s. FASEB J. 2005 Oct;19(12):1743-5. doi: 10.1096/fj.05-3936fje. Epub 2005 Jul 21. FASEB J. 2005. PMID: 16037096
Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16.
Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Fujiwara RT, et al. Among authors: lustigman s. Clin Vaccine Immunol. 2007 Mar;14(3):281-7. doi: 10.1128/CVI.00404-06. Epub 2007 Jan 31. Clin Vaccine Immunol. 2007. PMID: 17267592 Free PMC article.
Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus.
Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, Ranjit N, Lustigman S, Oksov Y, Hotez P. Zhan B, et al. Among authors: lustigman s. Infect Immun. 2010 Apr;78(4):1552-63. doi: 10.1128/IAI.00848-09. Epub 2010 Feb 9. Infect Immun. 2010. PMID: 20145100 Free PMC article.
Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection.
Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Arumugam S, et al. Among authors: lustigman s. PLoS Negl Trop Dis. 2016 Apr 5;10(4):e0004586. doi: 10.1371/journal.pntd.0004586. eCollection 2016 Apr. PLoS Negl Trop Dis. 2016. PMID: 27045170 Free PMC article.
Human anthelminthic vaccines: Rationale and challenges.
Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Hotez PJ, et al. Among authors: lustigman s. Vaccine. 2016 Jun 24;34(30):3549-55. doi: 10.1016/j.vaccine.2016.03.112. Epub 2016 May 9. Vaccine. 2016. PMID: 27171753
The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice.
Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Hess JA, et al. Among authors: lustigman s. PLoS Negl Trop Dis. 2016 Jul 7;10(7):e0004797. doi: 10.1371/journal.pntd.0004797. eCollection 2016 Jul. PLoS Negl Trop Dis. 2016. PMID: 27387453 Free PMC article.
Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.
George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. George PJ, et al. Among authors: lustigman s. PLoS Negl Trop Dis. 2019 Sep 16;13(9):e0007730. doi: 10.1371/journal.pntd.0007730. eCollection 2019 Sep. PLoS Negl Trop Dis. 2019. PMID: 31525197 Free PMC article.
Calling for rapid development of a safe and effective MERS vaccine.
Hotez PJ, Bottazzi ME, Tseng CT, Zhan B, Lustigman S, Du L, Jiang S. Hotez PJ, et al. Among authors: lustigman s. Microbes Infect. 2014 Jul;16(7):529-31. doi: 10.1016/j.micinf.2014.05.002. Epub 2014 Jun 12. Microbes Infect. 2014. PMID: 24931059 Free PMC article.
180 results