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Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands.
Conforti R, Ma Y, Morel Y, Paturel C, Terme M, Viaud S, Ryffel B, Ferrantini M, Uppaluri R, Schreiber R, Combadière C, Chaput N, André F, Kroemer G, Zitvogel L. Conforti R, et al. Among authors: combadiere c. Cancer Res. 2010 Jan 15;70(2):490-500. doi: 10.1158/0008-5472.CAN-09-1890. Epub 2010 Jan 12. Cancer Res. 2010. PMID: 20068181
Ly6Chigh Monocytes Protect against Kidney Damage during Sepsis via a CX3CR1-Dependent Adhesion Mechanism.
Chousterman BG, Boissonnas A, Poupel L, Baudesson de Chanville C, Adam J, Tabibzadeh N, Licata F, Lukaszewicz AC, Lombès A, Deterre P, Payen D, Combadière C. Chousterman BG, et al. Among authors: combadiere c. J Am Soc Nephrol. 2016 Mar;27(3):792-803. doi: 10.1681/ASN.2015010009. Epub 2015 Jul 9. J Am Soc Nephrol. 2016. PMID: 26160897 Free PMC article.
CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration.
Combadière C, Feumi C, Raoul W, Keller N, Rodéro M, Pézard A, Lavalette S, Houssier M, Jonet L, Picard E, Debré P, Sirinyan M, Deterre P, Ferroukhi T, Cohen SY, Chauvaud D, Jeanny JC, Chemtob S, Behar-Cohen F, Sennlaub F. Combadière C, et al. J Clin Invest. 2007 Oct;117(10):2920-8. doi: 10.1172/JCI31692. J Clin Invest. 2007. PMID: 17909628 Free PMC article.
Lipid-bloated subretinal microglial cells are at the origin of drusen appearance in CX3CR1-deficient mice.
Raoul W, Feumi C, Keller N, Lavalette S, Houssier M, Behar-Cohen F, Combadière C, Sennlaub F. Raoul W, et al. Among authors: combadiere c. Ophthalmic Res. 2008;40(3-4):115-9. doi: 10.1159/000119860. Epub 2008 Apr 18. Ophthalmic Res. 2008. PMID: 18421223 Free PMC article.
We demonstrate that the anatomical equivalent of the drusen-like appearance in these mice are lipid-bloated subretinal microglial cells rather than subretinal pigment epithelium deposits [Combadiere C, et al: J Clin Invest 2007;117:2920-2928]....
We demonstrate that the anatomical equivalent of the drusen-like appearance in these mice are lipid-bloated subretinal microglial cells rath …
Deleterious genetic influence of CX3CR1 genotypes on HIV-1 disease progression.
Faure S, Meyer L, Genin E, Pellet P, Debré P, Théodorou I, Combadière C; SEROCO Study Group. Faure S, et al. Among authors: combadiere c. J Acquir Immune Defic Syndr. 2003 Mar 1;32(3):335-7. doi: 10.1097/00126334-200303010-00014. J Acquir Immune Defic Syndr. 2003. PMID: 12626895
152 results