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Bcl-2 changes conformation to inhibit Bax oligomerization.
Dlugosz PJ, Billen LP, Annis MG, Zhu W, Zhang Z, Lin J, Leber B, Andrews DW. Dlugosz PJ, et al. Among authors: annis mg. EMBO J. 2006 Jun 7;25(11):2287-96. doi: 10.1038/sj.emboj.7601126. Epub 2006 Apr 27. EMBO J. 2006. PMID: 16642033 Free PMC article.
Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax.
Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J. Zhang Z, et al. Among authors: annis mg. J Biol Chem. 2004 Oct 15;279(42):43920-8. doi: 10.1074/jbc.M406412200. Epub 2004 Aug 9. J Biol Chem. 2004. PMID: 15302859 Free PMC article.
Grb10 and active Raf-1 kinase promote Bad-dependent cell survival.
Kebache S, Ash J, Annis MG, Hagan J, Huber M, Hassard J, Stewart CL, Whiteway M, Nantel A. Kebache S, et al. Among authors: annis mg. J Biol Chem. 2007 Jul 27;282(30):21873-83. doi: 10.1074/jbc.M611066200. Epub 2007 May 29. J Biol Chem. 2007. PMID: 17535812 Free article.
44 results