Lehrer RI - Search Results

1

Theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation.

Gallo SA, Wang W, Rawat SS, Jung G, Waring AJ, Cole AM, Lu H, Yan X, Daly NL, Craik DJ, Jiang S, Lehrer RI, Blumenthal R. Gallo SA, et al. Among authors: lehrer ri. J Biol Chem. 2006 Jul 7;281(27):18787-92. doi: 10.1074/jbc.M602422200. Epub 2006 Apr 28. J Biol Chem. 2006. PMID: 16648135 Free article.

2

Activity of alpha- and theta-defensins against primary isolates of HIV-1.

Wang W, Owen SM, Rudolph DL, Cole AM, Hong T, Waring AJ, Lal RB, Lehrer RI. Wang W, et al. Among authors: lehrer ri. J Immunol. 2004 Jul 1;173(1):515-20. doi: 10.4049/jimmunol.173.1.515. J Immunol. 2004. PMID: 15210812

3

Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins.

Leikina E, Delanoe-Ayari H, Melikov K, Cho MS, Chen A, Waring AJ, Wang W, Xie Y, Loo JA, Lehrer RI, Chernomordik LV. Leikina E, et al. Among authors: lehrer ri. Nat Immunol. 2005 Oct;6(10):995-1001. doi: 10.1038/ni1248. Epub 2005 Sep 11. Nat Immunol. 2005. PMID: 16155572 Free article.

4

HIV-1 adapts to a retrocyclin with cationic amino acid substitutions that reduce fusion efficiency of gp41.

Cole AL, Yang OO, Warren AD, Waring AJ, Lehrer RI, Cole AM. Cole AL, et al. Among authors: lehrer ri. J Immunol. 2006 Jun 1;176(11):6900-5. doi: 10.4049/jimmunol.176.11.6900. J Immunol. 2006. PMID: 16709850

5

Retrocyclins kill bacilli and germinating spores of Bacillus anthracis and inactivate anthrax lethal toxin.

Wang W, Mulakala C, Ward SC, Jung G, Luong H, Pham D, Waring AJ, Kaznessis Y, Lu W, Bradley KA, Lehrer RI. Wang W, et al. Among authors: lehrer ri. J Biol Chem. 2006 Oct 27;281(43):32755-64. doi: 10.1074/jbc.M603614200. Epub 2006 Jun 21. J Biol Chem. 2006. PMID: 16790431 Free PMC article.

6

Paradoxical effects of two theta-defensins on HIV type 1 infection.

Wang Q, Wang W, Zheng J, Tabibian S, Xie Y, Song J, Waring AJ, Chiu R, Yang OO, Chen IS, Lehrer RI, Pang S. Wang Q, et al. Among authors: lehrer ri. AIDS Res Hum Retroviruses. 2007 Apr;23(4):508-14. doi: 10.1089/aid.2006.0119. AIDS Res Hum Retroviruses. 2007. PMID: 17506607

7

Retrocyclin-2: structural analysis of a potent anti-HIV theta-defensin.

Daly NL, Chen YK, Rosengren KJ, Marx UC, Phillips ML, Waring AJ, Wang W, Lehrer RI, Craik DJ. Daly NL, et al. Among authors: lehrer ri. Biochemistry. 2007 Sep 4;46(35):9920-8. doi: 10.1021/bi700720e. Epub 2007 Aug 8. Biochemistry. 2007. PMID: 17685559

8

Retrocyclin RC-101 overcomes cationic mutations on the heptad repeat 2 region of HIV-1 gp41.

Fuhrman CA, Warren AD, Waring AJ, Dutz SM, Sharma S, Lehrer RI, Cole AL, Cole AM. Fuhrman CA, et al. Among authors: lehrer ri. FEBS J. 2007 Dec;274(24):6477-87. doi: 10.1111/j.1742-4658.2007.06165.x. Epub 2007 Nov 19. FEBS J. 2007. PMID: 18028423 Free article.

9

Trp-26 imparts functional versatility to human alpha-defensin HNP1.

Wei G, Pazgier M, de Leeuw E, Rajabi M, Li J, Zou G, Jung G, Yuan W, Lu WY, Lehrer RI, Lu W. Wei G, et al. Among authors: lehrer ri. J Biol Chem. 2010 May 21;285(21):16275-85. doi: 10.1074/jbc.M110.102749. Epub 2010 Mar 10. J Biol Chem. 2010. PMID: 20220136 Free PMC article.

10

Sometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptide.

Pazgier M, Wei G, Ericksen B, Jung G, Wu Z, de Leeuw E, Yuan W, Szmacinski H, Lu WY, Lubkowski J, Lehrer RI, Lu W. Pazgier M, et al. Among authors: lehrer ri. J Biol Chem. 2012 Mar 16;287(12):8944-53. doi: 10.1074/jbc.M111.332205. Epub 2012 Jan 23. J Biol Chem. 2012. PMID: 22270360 Free PMC article.

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