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Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
Bosch J, Robien MA, Mehlin C, Boni E, Riechers A, Buckner FS, Van Voorhis WC, Myler PJ, Worthey EA, DeTitta G, Luft JR, Lauricella A, Gulde S, Anderson LA, Kalyuzhniy O, Neely HM, Ross J, Earnest TN, Soltis M, Schoenfeld L, Zucker F, Merritt EA, Fan E, Verlinde CL, Hol WG. Bosch J, et al. Among authors: riechers a. J Med Chem. 2006 Oct 5;49(20):5939-46. doi: 10.1021/jm060429m. J Med Chem. 2006. PMID: 17004709
Glycogen synthase kinase 3 is a potential drug target for African trypanosomiasis therapy.
Ojo KK, Gillespie JR, Riechers AJ, Napuli AJ, Verlinde CL, Buckner FS, Gelb MH, Domostoj MM, Wells SJ, Scheer A, Wells TN, Van Voorhis WC. Ojo KK, et al. Among authors: riechers aj. Antimicrob Agents Chemother. 2008 Oct;52(10):3710-7. doi: 10.1128/AAC.00364-08. Epub 2008 Jul 21. Antimicrob Agents Chemother. 2008. PMID: 18644955 Free PMC article.
Genomic-scale prioritization of drug targets: the TDR Targets database.
Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL. Agüero F, et al. Among authors: riechers a. Nat Rev Drug Discov. 2008 Nov;7(11):900-7. doi: 10.1038/nrd2684. Epub 2008 Oct 17. Nat Rev Drug Discov. 2008. PMID: 18927591 Free PMC article. Review.
MIA--a new target protein for malignant melanoma therapy.
Schmidt J, Riechers A, Bosserhoff AK. Schmidt J, et al. Among authors: riechers a. Histol Histopathol. 2013 Apr;28(4):421-6. doi: 10.14670/HH-28.421. Epub 2012 Nov 22. Histol Histopathol. 2013. PMID: 23192727 Review.
18 results