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Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Chamian F, et al. Among authors: cardinale i. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2075-80. doi: 10.1073/pnas.0409569102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671179 Free PMC article. Clinical Trial.
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, Krueger JG. Lowes MA, et al. Among authors: cardinale i. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19057-62. doi: 10.1073/pnas.0509736102. Proc Natl Acad Sci U S A. 2005. PMID: 16380428 Free PMC article.
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.
Lowes MA, Kikuchi T, Fuentes-Duculan J, Cardinale I, Zaba LC, Haider AS, Bowman EP, Krueger JG. Lowes MA, et al. Among authors: cardinale i. J Invest Dermatol. 2008 May;128(5):1207-11. doi: 10.1038/sj.jid.5701213. Epub 2008 Jan 17. J Invest Dermatol. 2008. PMID: 18200064 Free article.
Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis.
Haider AS, Lowes MA, Suárez-Fariñas M, Zaba LC, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Haider AS, et al. Among authors: cardinale i. J Immunol. 2008 Feb 1;180(3):1913-20. doi: 10.4049/jimmunol.180.3.1913. J Immunol. 2008. PMID: 18209089 Clinical Trial.
Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.
Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG. Guttman-Yassky E, et al. Among authors: cardinale i. J Immunol. 2008 Nov 15;181(10):7420-7. doi: 10.4049/jimmunol.181.10.7420. J Immunol. 2008. PMID: 18981165 Free PMC article.
IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.
Nograles KE, Zaba LC, Shemer A, Fuentes-Duculan J, Cardinale I, Kikuchi T, Ramon M, Bergman R, Krueger JG, Guttman-Yassky E. Nograles KE, et al. Among authors: cardinale i. J Allergy Clin Immunol. 2009 Jun;123(6):1244-52.e2. doi: 10.1016/j.jaci.2009.03.041. Epub 2009 May 12. J Allergy Clin Immunol. 2009. PMID: 19439349 Free PMC article.
51 results