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The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Jones RG, Bui T, White C, Madesh M, Krawczyk CM, Lindsten T, Hawkins BJ, Kubek S, Frauwirth KA, Wang YL, Conway SJ, Roderick HL, Bootman MD, Shen H, Foskett JK, Thompson CB. Jones RG, et al. Among authors: shen h. Immunity. 2007 Aug;27(2):268-80. doi: 10.1016/j.immuni.2007.05.023. Epub 2007 Aug 9. Immunity. 2007. PMID: 17692540 Free PMC article.
Control of effector CD8+ T cell function by the transcription factor Eomesodermin.
Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, Zediak VP, Banica M, DiCioccio CB, Gross DA, Mao CA, Shen H, Cereb N, Yang SY, Lindsten T, Rossant J, Hunter CA, Reiner SL. Pearce EL, et al. Among authors: shen h. Science. 2003 Nov 7;302(5647):1041-3. doi: 10.1126/science.1090148. Science. 2003. PMID: 14605368
Th1 and Th2 cells help CD8 T-cell responses.
Ekkens MJ, Shedlock DJ, Jung E, Troy A, Pearce EL, Shen H, Pearce EJ. Ekkens MJ, et al. Among authors: shen h. Infect Immun. 2007 May;75(5):2291-6. doi: 10.1128/IAI.01328-06. Epub 2007 Feb 26. Infect Immun. 2007. PMID: 17325050 Free PMC article.
Memory CD4 T cells enhance primary CD8 T-cell responses.
Krawczyk CM, Shen H, Pearce EJ. Krawczyk CM, et al. Among authors: shen h. Infect Immun. 2007 Jul;75(7):3556-60. doi: 10.1128/IAI.00086-07. Epub 2007 Apr 16. Infect Immun. 2007. PMID: 17438031 Free PMC article.
Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
Pearce EL, Walsh MC, Cejas PJ, Harms GM, Shen H, Wang LS, Jones RG, Choi Y. Pearce EL, et al. Among authors: shen h. Nature. 2009 Jul 2;460(7251):103-7. doi: 10.1038/nature08097. Epub 2009 Jun 3. Nature. 2009. PMID: 19494812 Free PMC article.
Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.
Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, Wu GD, Choi Y. Han D, et al. Among authors: shen h. Immunity. 2013 Jun 27;38(6):1211-22. doi: 10.1016/j.immuni.2013.05.012. Epub 2013 Jun 20. Immunity. 2013. PMID: 23791643 Free PMC article.
Bystander chronic infection negatively impacts development of CD8(+) T cell memory.
Stelekati E, Shin H, Doering TA, Dolfi DV, Ziegler CG, Beiting DP, Dawson L, Liboon J, Wolski D, Ali MA, Katsikis PD, Shen H, Roos DS, Haining WN, Lauer GM, Wherry EJ. Stelekati E, et al. Among authors: shen h. Immunity. 2014 May 15;40(5):801-13. doi: 10.1016/j.immuni.2014.04.010. Immunity. 2014. PMID: 24837104 Free PMC article.
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