Young DW - Search Results

1

Integrating high-content screening and ligand-target prediction to identify mechanism of action.

Young DW, Bender A, Hoyt J, McWhinnie E, Chirn GW, Tao CY, Tallarico JA, Labow M, Jenkins JL, Mitchison TJ, Feng Y. Young DW, et al. Nat Chem Biol. 2008 Jan;4(1):59-68. doi: 10.1038/nchembio.2007.53. Epub 2007 Dec 9. Nat Chem Biol. 2008. PMID: 18066055

2

Chemogenomic data analysis: prediction of small-molecule targets and the advent of biological fingerprint.

Bender A, Young DW, Jenkins JL, Serrano M, Mikhailov D, Clemons PA, Davies JW. Bender A, et al. Among authors: young dw. Comb Chem High Throughput Screen. 2007 Sep;10(8):719-31. doi: 10.2174/138620707782507313. Comb Chem High Throughput Screen. 2007. PMID: 18045083 Review.

3

Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds.

Feng Y, Mitchison TJ, Bender A, Young DW, Tallarico JA. Feng Y, et al. Among authors: young dw. Nat Rev Drug Discov. 2009 Jul;8(7):567-78. doi: 10.1038/nrd2876. Nat Rev Drug Discov. 2009. PMID: 19568283 Review.

4

Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.

Young DW, Hassan MQ, Pratap J, Galindo M, Zaidi SK, Lee SH, Yang X, Xie R, Javed A, Underwood JM, Furcinitti P, Imbalzano AN, Penman S, Nickerson JA, Montecino MA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Young DW, et al. Nature. 2007 Jan 25;445(7126):442-6. doi: 10.1038/nature05473. Nature. 2007. PMID: 17251981

5

Mitotic bookmarking of genes: a novel dimension to epigenetic control.

Zaidi SK, Young DW, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Zaidi SK, et al. Among authors: young dw. Nat Rev Genet. 2010 Aug;11(8):583-9. doi: 10.1038/nrg2827. Epub 2010 Jul 13. Nat Rev Genet. 2010. PMID: 20628351 Free PMC article. Review.

6

Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.

Young DW, Zaidi SK, Furcinitti PS, Javed A, van Wijnen AJ, Stein JL, Lian JB, Stein GS. Young DW, et al. J Cell Sci. 2004 Oct 1;117(Pt 21):4889-96. doi: 10.1242/jcs.01229. Epub 2004 Sep 14. J Cell Sci. 2004. PMID: 15367579

7

Nuclear microenvironments in biological control and cancer.

Zaidi SK, Young DW, Javed A, Pratap J, Montecino M, van Wijnen A, Lian JB, Stein JL, Stein GS. Zaidi SK, et al. Among authors: young dw. Nat Rev Cancer. 2007 Jun;7(6):454-63. doi: 10.1038/nrc2149. Nat Rev Cancer. 2007. PMID: 17522714 Review.

8

The dynamic organization of gene-regulatory machinery in nuclear microenvironments.

Zaidi SK, Young DW, Choi JY, Pratap J, Javed A, Montecino M, Stein JL, van Wijnen AJ, Lian JB, Stein GS. Zaidi SK, et al. Among authors: young dw. EMBO Rep. 2005 Feb;6(2):128-33. doi: 10.1038/sj.embor.7400337. EMBO Rep. 2005. PMID: 15689940 Free PMC article. Review.

9

Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.

van der Deen M, Hassan MQ, Pratap J, Teplyuk NM, Young DW, Javed A, Zaidi SK, Lian JB, Montecino M, Stein JL, Stein GS, van Wijnen AJ. van der Deen M, et al. Among authors: young dw. Methods Mol Biol. 2008;455:165-76. doi: 10.1007/978-1-59745-104-8_13. Methods Mol Biol. 2008. PMID: 18463819

10

Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.

Stein GS, Zaidi SK, Stein JL, Lian JB, van Wijnen AJ, Montecino M, Young DW, Javed A, Pratap J, Choi JY, Ali SA, Pande S, Hassan MQ. Stein GS, et al. Among authors: young dw. Biochem Cell Biol. 2009 Feb;87(1):1-6. doi: 10.1139/O08-094. Biochem Cell Biol. 2009. PMID: 19234518 Free PMC article. Review.

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