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Identification of cellular pathways of "type 1," Th17 T cells, and TNF- and inducible nitric oxide synthase-producing dendritic cells in autoimmune inflammation through pharmacogenomic study of cyclosporine A in psoriasis.
Haider AS, Lowes MA, Suárez-Fariñas M, Zaba LC, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Haider AS, et al. Among authors: wittkowski km. J Immunol. 2008 Feb 1;180(3):1913-20. doi: 10.4049/jimmunol.180.3.1913. J Immunol. 2008. PMID: 18209089 Clinical Trial.
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Chamian F, et al. Among authors: wittkowski km. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2075-80. doi: 10.1073/pnas.0409569102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671179 Free PMC article. Clinical Trial.
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a).
Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R, Novitskaya I, Carbonaro H, Cardinale I, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Wittkowski KM, Papp K, Garovoy M, Dummer W, Steinman RM, Krueger JG. Lowes MA, et al. Among authors: wittkowski km. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19057-62. doi: 10.1073/pnas.0509736102. Proc Natl Acad Sci U S A. 2005. PMID: 16380428 Free PMC article.
Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis.
Chamian F, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG, Lowes MA. Chamian F, et al. Among authors: wittkowski km. J Transl Med. 2007 Jun 7;5:27. doi: 10.1186/1479-5876-5-27. J Transl Med. 2007. PMID: 17555598 Free PMC article. Clinical Trial.
"Harshlighting" small blemishes on microarrays.
Suárez-Fariñas M, Haider A, Wittkowski KM. Suárez-Fariñas M, et al. Among authors: wittkowski km. BMC Bioinformatics. 2005 Mar 22;6:65. doi: 10.1186/1471-2105-6-65. BMC Bioinformatics. 2005. PMID: 15784152 Free PMC article.
Bioinformatics tools enabling u-statistics for microarrays.
Wittkowski KM, Haider A, Sehayek E, Suárez-Fariñas M, Pellegrino M, Peshansky A, Coffran C, Coker S. Wittkowski KM, et al. Conf Proc IEEE Eng Med Biol Soc. 2006;2006:3464-9. doi: 10.1109/IEMBS.2006.260846. Conf Proc IEEE Eng Med Biol Soc. 2006. PMID: 17947031 Free PMC article.
Harshlight: a "corrective make-up" program for microarray chips.
Suárez-Fariñas M, Pellegrino M, Wittkowski KM, Magnasco MO. Suárez-Fariñas M, et al. Among authors: wittkowski km. BMC Bioinformatics. 2005 Dec 10;6:294. doi: 10.1186/1471-2105-6-294. BMC Bioinformatics. 2005. PMID: 16336691 Free PMC article.
68 results