Duff K - Search Results

1

New directions for frontotemporal dementia drug discovery.

Trojanowski JQ, Duff K, Fillit H, Koroshetz W, Kuret J, Murphy D, Refolo L; Frontotemporal Dementia (FTD) Working Group on FTD Drug Discovery. Trojanowski JQ, et al. Among authors: duff k. Alzheimers Dement. 2008 Mar;4(2):89-93. doi: 10.1016/j.jalz.2007.06.001. Epub 2007 Sep 10. Alzheimers Dement. 2008. PMID: 18631953 Free PMC article.

2

Disaggregation of tau as a therapeutic approach to tauopathies.

Duff K, Kuret J, Congdon EE. Duff K, et al. Curr Alzheimer Res. 2010 May;7(3):235-40. doi: 10.2174/156720510791050885. Curr Alzheimer Res. 2010. PMID: 20088807

3

Inhibition of tau polymerization with a cyanine dye in two distinct model systems.

Congdon EE, Figueroa YH, Wang L, Toneva G, Chang E, Kuret J, Conrad C, Duff KE. Congdon EE, et al. J Biol Chem. 2009 Jul 31;284(31):20830-9. doi: 10.1074/jbc.M109.016089. Epub 2009 May 28. J Biol Chem. 2009. PMID: 19478088 Free PMC article.

4

Structure-activity relationship of cyanine tau aggregation inhibitors.

Chang E, Congdon EE, Honson NS, Duff KE, Kuret J. Chang E, et al. J Med Chem. 2009 Jun 11;52(11):3539-47. doi: 10.1021/jm900116d. J Med Chem. 2009. PMID: 19432420 Free PMC article.

5

Wolframin is a novel regulator of tau pathology and neurodegeneration.

Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, Wemlinger T, Wu M, Kokiko-Cochran ON, Popovich P, Flowers XE, Honig LS, Vonsattel JP, Scharre DW, Beach TG, Ma Q, Kuret J, Kõks S, Urano F, Duff KE, Fu H. Chen S, et al. Acta Neuropathol. 2022 May;143(5):547-569. doi: 10.1007/s00401-022-02417-4. Epub 2022 Apr 7. Acta Neuropathol. 2022. PMID: 35389045

6

Modulation of A(beta) peptides by estrogen in mouse models.

Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Zheng H, et al. Among authors: duff k. J Neurochem. 2002 Jan;80(1):191-6. doi: 10.1046/j.0022-3042.2001.00690.x. J Neurochem. 2002. PMID: 11796757 Free article.

7

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Refolo LM, Pappolla MA, LaFrancois J, Malester B, Schmidt SD, Thomas-Bryant T, Tint GS, Wang R, Mercken M, Petanceska SS, Duff KE. Refolo LM, et al. Among authors: duff ke. Neurobiol Dis. 2001 Oct;8(5):890-9. doi: 10.1006/nbdi.2001.0422. Neurobiol Dis. 2001. PMID: 11592856

8

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.

Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479

9

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA. Refolo LM, et al. Among authors: duff k. Neurobiol Dis. 2000 Aug;7(4):321-31. doi: 10.1006/nbdi.2000.0304. Neurobiol Dis. 2000. PMID: 10964604

10

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. Mehta ND, et al. Among authors: duff k. Ann Neurol. 1998 Feb;43(2):256-8. doi: 10.1002/ana.410430217. Ann Neurol. 1998. PMID: 9485068

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