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Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N. Narimatsu S, et al. Among authors: kumamoto t. Biochem Pharmacol. 2006 Apr 28;71(9):1377-85. doi: 10.1016/j.bcp.2006.01.015. Epub 2006 Feb 28. Biochem Pharmacol. 2006. PMID: 16510126
Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N. Narimatsu S, et al. Among authors: kumamoto t. Biochem Pharmacol. 2008 Feb 1;75(3):752-60. doi: 10.1016/j.bcp.2007.09.019. Epub 2007 Sep 29. Biochem Pharmacol. 2008. PMID: 17980859
This metabolic profile is different from our previous findings in human liver microsomal fractions, in which the aromatic ring O-demethylation was the major pathway whereas the side-chain N-deisopropylation was minor [Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto …
This metabolic profile is different from our previous findings in human liver microsomal fractions, in which the aromatic ring O-demethylati …
Optical resolution of (+/-)-1,2-Bis(2-methylphenyl)ethylene-1,2-diamine as a chiral framework for 2-iminoimidazolidine with 2-methylphenyl pendant and the guanidine-catalyzed asymmetric michael reaction of tert-butyl diphenyliminoacetate and ethyl acrylate.
Ryoda A, Yajima N, Haga T, Kumamoto T, Nakanishi W, Kawahata M, Yamaguchi K, Ishikawa T. Ryoda A, et al. Among authors: kumamoto t. J Org Chem. 2008 Jan 4;73(1):133-41. doi: 10.1021/jo701923z. Epub 2007 Dec 7. J Org Chem. 2008. PMID: 18062699
The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
Narimatsu S, Kiryu K, Yonemoto R, Yoshino M, Kobatake M, Kazamori D, Hagino S, Masuda K, Katsu T, Asanuma M, Kumamoto T, Ishikawa T, Funae Y, Yamano S, Hanioka N, Naito S. Narimatsu S, et al. Among authors: kumamoto t. Chem Biol Interact. 2008 Mar 10;172(1):11-21. doi: 10.1016/j.cbi.2007.11.010. Epub 2007 Nov 28. Chem Biol Interact. 2008. PMID: 18191824
620 results