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Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.
Benndorf RA, Schwedhelm E, Gnann A, Taheri R, Kom G, Didié M, Steenpass A, Ergün S, Böger RH. Benndorf RA, et al. Among authors: boger rh. Circ Res. 2008 Oct 24;103(9):1037-46. doi: 10.1161/CIRCRESAHA.108.184036. Epub 2008 Sep 18. Circ Res. 2008. PMID: 18802021
321 results