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The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.
Shema E, Tirosh I, Aylon Y, Huang J, Ye C, Moskovits N, Raver-Shapira N, Minsky N, Pirngruber J, Tarcic G, Hublarova P, Moyal L, Gana-Weisz M, Shiloh Y, Yarden Y, Johnsen SA, Vojtesek B, Berger SL, Oren M. Shema E, et al. Among authors: berger sl. Genes Dev. 2008 Oct 1;22(19):2664-76. doi: 10.1101/gad.1703008. Genes Dev. 2008. PMID: 18832071 Free PMC article.
An operational definition of epigenetics.
Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. Berger SL, et al. Genes Dev. 2009 Apr 1;23(7):781-3. doi: 10.1101/gad.1787609. Genes Dev. 2009. PMID: 19339683 Free PMC article.
G9a and Glp methylate lysine 373 in the tumor suppressor p53.
Huang J, Dorsey J, Chuikov S, Zhang X, Jenuwein T, Reinberg D, Berger SL. Huang J, et al. Among authors: berger sl. J Biol Chem. 2010 Mar 26;285(13):9636-9641. doi: 10.1074/jbc.M109.062588. Epub 2010 Jan 29. J Biol Chem. 2010. PMID: 20118233 Free PMC article.
311 results