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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1.
Sablin EP, Woods A, Krylova IN, Hwang P, Ingraham HA, Fletterick RJ. Sablin EP, et al. Among authors: hwang p. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18390-5. doi: 10.1073/pnas.0808936105. Epub 2008 Nov 17. Proc Natl Acad Sci U S A. 2008. PMID: 19015525 Free PMC article.
Structure-based discovery of antagonists of nuclear receptor LRH-1.
Benod C, Carlsson J, Uthayaruban R, Hwang P, Irwin JJ, Doak AK, Shoichet BK, Sablin EP, Fletterick RJ. Benod C, et al. Among authors: hwang p. J Biol Chem. 2013 Jul 5;288(27):19830-44. doi: 10.1074/jbc.M112.411686. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23667258 Free PMC article.
The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.
Benod C, Villagomez R, Filgueira CS, Hwang PK, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P. Benod C, et al. Among authors: hwang pk. PLoS One. 2014 Jun 17;9(6):e99440. doi: 10.1371/journal.pone.0099440. eCollection 2014. PLoS One. 2014. PMID: 24936658 Free PMC article.
Mechanism of regulation in yeast glycogen phosphorylase.
Lin K, Hwang PK, Fletterick RJ. Lin K, et al. Among authors: hwang pk. J Biol Chem. 1995 Nov 10;270(45):26833-9. doi: 10.1074/jbc.270.45.26833. J Biol Chem. 1995. PMID: 7592925 Free article.
1,095 results