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Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
Stewart KD, Huth JR, Ng TI, McDaniel K, Hutchinson RN, Stoll VS, Mendoza RR, Matayoshi ED, Carrick R, Mo H, Severin J, Walter K, Richardson PL, Barrett LW, Meadows R, Anderson S, Kohlbrenner W, Maring C, Kempf DJ, Molla A, Olejniczak ET. Stewart KD, et al. Among authors: maring c. Bioorg Med Chem Lett. 2010 Jan 15;20(2):612-7. doi: 10.1016/j.bmcl.2009.11.076. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 20004576
Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors.
Maring CJ, Stoll VS, Zhao C, Sun M, Krueger AC, Stewart KD, Madigan DL, Kati WM, Xu Y, Carrick RJ, Montgomery DA, Kempf-Grote A, Marsh KC, Molla A, Steffy KR, Sham HL, Laver WG, Gu YG, Kempf DJ, Kohlbrenner WE. Maring CJ, et al. J Med Chem. 2005 Jun 16;48(12):3980-90. doi: 10.1021/jm049276y. J Med Chem. 2005. PMID: 15943472
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives.
Krueger AC, Madigan DL, Green BE, Hutchinson DK, Jiang WW, Kati WM, Liu Y, Maring CJ, Masse SV, McDaniel KF, Middleton TR, Mo H, Molla A, Montgomery DA, Ng TI, Kempf DJ. Krueger AC, et al. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2289-92. doi: 10.1016/j.bmcl.2007.01.072. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17300933
Synthesis of potent pyrrolidine influenza neuraminidase inhibitors.
Krueger AC, Xu Y, Kati WM, Kempf DJ, Maring CJ, McDaniel KF, Molla A, Montgomery D, Kohlbrenner WE. Krueger AC, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1692-5. doi: 10.1016/j.bmcl.2008.01.048. Epub 2008 Jan 18. Bioorg Med Chem Lett. 2008. PMID: 18242993
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides.
Krueger AC, Madigan DL, Jiang WW, Kati WM, Liu D, Liu Y, Maring CJ, Masse S, McDaniel KF, Middleton T, Mo H, Molla A, Montgomery D, Pratt JK, Rockway TW, Zhang R, Kempf DJ. Krueger AC, et al. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3367-70. doi: 10.1016/j.bmcl.2006.04.015. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650764
Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-benzyl and N-1-[3-methylbutyl]-4-hydroxy-1,8-naphthyridon-3-yl benzothiadiazine analogs containing substituents on the aromatic ring.
Rockway TW, Zhang R, Liu D, Betebenner DA, McDaniel KF, Pratt JK, Beno D, Montgomery D, Jiang WW, Masse S, Kati WM, Middleton T, Molla A, Maring CJ, Kempf DJ. Rockway TW, et al. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3833-8. doi: 10.1016/j.bmcl.2006.04.022. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16650984
36 results