Meadows R - Search Results

1

Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.

Stewart KD, Huth JR, Ng TI, McDaniel K, Hutchinson RN, Stoll VS, Mendoza RR, Matayoshi ED, Carrick R, Mo H, Severin J, Walter K, Richardson PL, Barrett LW, Meadows R, Anderson S, Kohlbrenner W, Maring C, Kempf DJ, Molla A, Olejniczak ET. Stewart KD, et al. Among authors: meadows r. Bioorg Med Chem Lett. 2010 Jan 15;20(2):612-7. doi: 10.1016/j.bmcl.2009.11.076. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 20004576

2

Non-peptidic small molecule inhibitors of XIAP.

Park CM, Sun C, Olejniczak ET, Wilson AE, Meadows RP, Betz SF, Elmore SW, Fesik SW. Park CM, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):771-5. doi: 10.1016/j.bmcl.2004.11.010. Bioorg Med Chem Lett. 2005. PMID: 15664855

3

Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization.

Sanders WJ, Nienaber VL, Lerner CG, McCall JO, Merrick SM, Swanson SJ, Harlan JE, Stoll VS, Stamper GF, Betz SF, Condroski KR, Meadows RP, Severin JM, Walter KA, Magdalinos P, Jakob CG, Wagner R, Beutel BA. Sanders WJ, et al. Among authors: meadows rp. J Med Chem. 2004 Mar 25;47(7):1709-18. doi: 10.1021/jm030497y. J Med Chem. 2004. PMID: 15027862

4

Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer.

Oost TK, Sun C, Armstrong RC, Al-Assaad AS, Betz SF, Deckwerth TL, Ding H, Elmore SW, Meadows RP, Olejniczak ET, Oleksijew A, Oltersdorf T, Rosenberg SH, Shoemaker AR, Tomaselli KJ, Zou H, Fesik SW. Oost TK, et al. Among authors: meadows rp. J Med Chem. 2004 Aug 26;47(18):4417-26. doi: 10.1021/jm040037k. J Med Chem. 2004. PMID: 15317454

5

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.

Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW. Petros AM, et al. Among authors: meadows rp. Protein Sci. 2000 Dec;9(12):2528-34. doi: 10.1110/ps.9.12.2528. Protein Sci. 2000. PMID: 11206074 Free PMC article.

6

A computer-based protocol for semiautomated assignments and 3D structure determination of proteins.

Meadows RP, Olejniczak ET, Fesik SW. Meadows RP, et al. J Biomol NMR. 1994 Jan;4(1):79-96. doi: 10.1007/BF00178337. J Biomol NMR. 1994. PMID: 7510556

7

Accurate measurement of H(N)-H(alpha) residual dipolar couplings in proteins.

Cai M, Wang H, Olejniczak ET, Meadows RP, Gunasekera AH, Xu N, Fesik SW. Cai M, et al. Among authors: meadows rp. J Magn Reson. 1999 Aug;139(2):451-3. doi: 10.1006/jmre.1999.1819. J Magn Reson. 1999. PMID: 10423386

8

Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR.

Meadows RP, Nettesheim DG, Xu RX, Olejniczak ET, Petros AM, Holzman TF, Severin J, Gubbins E, Smith H, Fesik SW. Meadows RP, et al. Biochemistry. 1993 Jan 26;32(3):754-65. doi: 10.1021/bi00054a004. Biochemistry. 1993. PMID: 7678499

9

An approach for high-throughput structure determination of proteins by NMR spectroscopy.

Medek A, Olejniczak ET, Meadows RP, Fesik SW. Medek A, et al. Among authors: meadows rp. J Biomol NMR. 2000 Nov;18(3):229-38. doi: 10.1023/a:1026544801001. J Biomol NMR. 2000. PMID: 11142513

10

1H, 13C, and 15N assignments and secondary structure of the FK506 binding protein when bound to ascomycin.

Xu RX, Nettesheim D, Olejniczak ET, Meadows R, Gemmecker G, Fesik SW. Xu RX, et al. Among authors: meadows r. Biopolymers. 1993 Apr;33(4):535-50. doi: 10.1002/bip.360330404. Biopolymers. 1993. PMID: 7682113

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

228 results

Search Page