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A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients.
Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. Kim KH, et al. Among authors: broadt tl. Hum Gene Ther. 2011 Jul;22(7):821-8. doi: 10.1089/hum.2010.180. Epub 2011 Mar 23. Hum Gene Ther. 2011. PMID: 21171861 Free PMC article.
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer.
Page JG, Tian B, Schweikart K, Tomaszewski J, Harris R, Broadt T, Polley-Nelson J, Noker PE, Wang M, Makhija S, Aurigemma R, Curiel DT, Alvarez RD. Page JG, et al. Am J Obstet Gynecol. 2007 Apr;196(4):389.e1-9; discussion 389.e9-10. doi: 10.1016/j.ajog.2006.12.016. Am J Obstet Gynecol. 2007. PMID: 17403430
Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in E. coli with stop codon optimization.
Vyas VV, Esposito D, Sumpter TL, Broadt TL, Hartley J, Knapp GC 4th, Cheng W, Jiang MS, Roach JM, Yang X, Giardina SL, Mitra G, Yovandich JL, Creekmore SP, Waldmann TA, Zhu J. Vyas VV, et al. Among authors: broadt tl. Biotechnol Prog. 2012 Mar-Apr;28(2):497-507. doi: 10.1002/btpr.746. Epub 2011 Dec 9. Biotechnol Prog. 2012. PMID: 22162520 Free PMC article.
Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging.
Pei J, Juniper G, van den Berg NS, Nisho N, Broadt T, Welch AR, Yi GS, Raymundo RC, Chirita SU, Lu G, Krishnan G, Lee YJ, Kapoor S, Zhou Q, Colevas AD, Lui NS, Poultsides GA, Li G, Zinn KR, Rosenthal EL. Pei J, et al. Mol Imaging Biol. 2021 Feb;23(1):109-116. doi: 10.1007/s11307-020-01536-2. Epub 2020 Sep 3. Mol Imaging Biol. 2021. PMID: 32880818 Free PMC article. Clinical Trial.