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A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients.
Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. Kim KH, et al. Among authors: peggins jo. Hum Gene Ther. 2011 Jul;22(7):821-8. doi: 10.1089/hum.2010.180. Epub 2011 Mar 23. Hum Gene Ther. 2011. PMID: 21171861 Free PMC article.
Evaluation of the safety and biodistribution of M032, an attenuated herpes simplex virus type 1 expressing hIL-12, after intracerebral administration to aotus nonhuman primates.
Roth JC, Cassady KA, Cody JJ, Parker JN, Price KH, Coleman JM, Peggins JO, Noker PE, Powers NW, Grimes SD, Carroll SL, Gillespie GY, Whitley RJ, Markert JM. Roth JC, et al. Among authors: peggins jo. Hum Gene Ther Clin Dev. 2014 Mar;25(1):16-27. doi: 10.1089/humc.2013.201. Hum Gene Ther Clin Dev. 2014. PMID: 24649838 Free PMC article.
Attenuation of neurovirulence, biodistribution, and shedding of a poliovirus:rhinovirus chimera after intrathalamic inoculation in Macaca fascicularis.
Dobrikova EY, Goetz C, Walters RW, Lawson SK, Peggins JO, Muszynski K, Ruppel S, Poole K, Giardina SL, Vela EM, Estep JE, Gromeier M. Dobrikova EY, et al. Among authors: peggins jo. J Virol. 2012 Mar;86(5):2750-9. doi: 10.1128/JVI.06427-11. Epub 2011 Dec 14. J Virol. 2012. PMID: 22171271 Free PMC article.
Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors.
Srivastava AK, Hollingshead MG, Govindharajulu JP, Covey JM, Liston D, Simpson MA, Peggins JO, Bottaro DP, Wright JJ, Kinders RJ, Doroshow JH, Parchment RE. Srivastava AK, et al. Among authors: peggins jo. Mol Cancer Ther. 2018 Mar;17(3):698-709. doi: 10.1158/1535-7163.MCT-17-0552. Epub 2018 Feb 14. Mol Cancer Ther. 2018. PMID: 29444985 Free PMC article.
Lack of toxicity of a STAT3 decoy oligonucleotide.
Sen M, Tosca PJ, Zwayer C, Ryan MJ, Johnson JD, Knostman KA, Giclas PC, Peggins JO, Tomaszewski JE, McMurray TP, Li C, Leibowitz MS, Ferris RL, Gooding WE, Thomas SM, Johnson DE, Grandis JR. Sen M, et al. Among authors: peggins jo. Cancer Chemother Pharmacol. 2009 May;63(6):983-95. doi: 10.1007/s00280-008-0823-6. Epub 2008 Sep 3. Cancer Chemother Pharmacol. 2009. PMID: 18766340 Free PMC article.
38 results