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Page 1
T cells fail to develop in the human skin-cell explants system; an inconvenient truth.
Meek B, Van Elssen CH, Huijskens MJ, van der Stegen SJ, Tonnaer S, Lumeij SB, Vanderlocht J, Kirkland MA, Hesselink R, Germeraad WT, Bos GM. Meek B, et al. Among authors: van der stegen sj, van elssen ch. BMC Immunol. 2011 Feb 18;12:17. doi: 10.1186/1471-2172-12-17. BMC Immunol. 2011. PMID: 21332988 Free PMC article.
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells.
van der Stegen SJC, Lindenbergh PL, Petrovic RM, Xie H, Diop MP, Alexeeva V, Shi Y, Mansilla-Soto J, Hamieh M, Eyquem J, Cabriolu A, Wang X, Abujarour R, Lee T, Clarke R, Valamehr B, Themeli M, Riviere I, Sadelain M. van der Stegen SJC, et al. Nat Biomed Eng. 2022 Nov;6(11):1284-1297. doi: 10.1038/s41551-022-00915-0. Epub 2022 Aug 8. Nat Biomed Eng. 2022. PMID: 35941192 Free PMC article.
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape.
Hamieh M, Dobrin A, Cabriolu A, van der Stegen SJC, Giavridis T, Mansilla-Soto J, Eyquem J, Zhao Z, Whitlock BM, Miele MM, Li Z, Cunanan KM, Huse M, Hendrickson RC, Wang X, Rivière I, Sadelain M. Hamieh M, et al. Among authors: van der stegen sjc. Nature. 2019 Apr;568(7750):112-116. doi: 10.1038/s41586-019-1054-1. Epub 2019 Mar 27. Nature. 2019. PMID: 30918399 Free PMC article.
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M. Eyquem J, et al. Among authors: van der stegen sj. Nature. 2017 Mar 2;543(7643):113-117. doi: 10.1038/nature21405. Epub 2017 Feb 22. Nature. 2017. PMID: 28225754 Free PMC article.
HLA-independent T cell receptors for targeting tumors with low antigen density.
Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M. Mansilla-Soto J, et al. Among authors: van der stegen sjc. Nat Med. 2022 Feb;28(2):345-352. doi: 10.1038/s41591-021-01621-1. Epub 2022 Jan 13. Nat Med. 2022. PMID: 35027758 Free PMC article.
CAR T-cell immunotherapy of MET-expressing malignant mesothelioma.
Thayaparan T, Petrovic RM, Achkova DY, Zabinski T, Davies DM, Klampatsa A, Parente-Pereira AC, Whilding LM, van der Stegen SJ, Woodman N, Sheaff M, Cochran JR, Spicer JF, Maher J. Thayaparan T, et al. Among authors: van der stegen sj. Oncoimmunology. 2017 Aug 14;6(12):e1363137. doi: 10.1080/2162402X.2017.1363137. eCollection 2017. Oncoimmunology. 2017. PMID: 29209570 Free PMC article.
Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity?
van der Stegen SJ, Davies DM, Wilkie S, Foster J, Sosabowski JK, Burnet J, Whilding LM, Petrovic RM, Ghaem-Maghami S, Mather S, Jeannon JP, Parente-Pereira AC, Maher J. van der Stegen SJ, et al. J Immunol. 2013 Nov 1;191(9):4589-98. doi: 10.4049/jimmunol.1301523. Epub 2013 Sep 23. J Immunol. 2013. PMID: 24062490
20 results