Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication.
Cencic R, Desforges M, Hall DR, Kozakov D, Du Y, Min J, Dingledine R, Fu H, Vajda S, Talbot PJ, Pelletier J.
Cencic R, et al.
J Virol. 2011 Jul;85(13):6381-9. doi: 10.1128/JVI.00078-11. Epub 2011 Apr 20.
J Virol. 2011.
PMID: 21507972
Free PMC article.
We recently reported on an ultrahigh-throughput screen to discover compounds that inhibit eIF4F activity by blocking the interaction of two of its subunits (R. Cencic et al., Proc. Natl. Acad. Sci. U. S. A. 108:1046-1051, 2011). ...
We recently reported on an ultrahigh-throughput screen to discover compounds that inhibit eIF4F activity by blocking the interaction of two …