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Natural products reveal cancer cell dependence on oxysterol-binding proteins.
Nat Chem Biol. 2011 Aug 7;7(9):639-47. doi: 10.1038/nchembio.625.
Nat Chem Biol. 2011.
PMID: 21822274
Free PMC article.
Kinase inhibitor profiling using chemoproteomics.
Schirle M, Petrella EC, Brittain SM, Schwalb D, Harrington E, Cornella-Taracido I, Tallarico JA.
Schirle M, et al.
Methods Mol Biol. 2012;795:161-77. doi: 10.1007/978-1-61779-337-0_11.
Methods Mol Biol. 2012.
PMID: 21960222
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Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF, Helliwell SB, D'Aquin S, Bastien J, Wang H, Wiederschain D, Kuerth J, Bergman P, Schwalb D, Thomas J, Ugwonali S, Harbinski F, Tallarico J, Wilson CJ, Myer VE, Porter JA, Bussiere DE, Finan PM, Labow MA, Mao X, Hamann LG, Manning BD, Valdez RA, Nicholson T, Schirle M, Knapp MS, Keaney EP, Murphy LO.
Dowdle WE, et al.
Nat Cell Biol. 2014 Nov;16(11):1069-79. doi: 10.1038/ncb3053. Epub 2014 Oct 19.
Nat Cell Biol. 2014.
PMID: 25327288
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Selective nitros(yl)ation induced in vivo by a nitric oxide-donating cyclooxygenase-2 inhibitor: a NObonomic analysis.
Dhawan V, Schwalb DJ, Shumway MJ, Warren MC, Wexler RS, Zemtseva IS, Zifcak BM, Janero DR.
Dhawan V, et al. Among authors: schwalb dj.
Free Radic Biol Med. 2005 Nov 1;39(9):1191-207. doi: 10.1016/j.freeradbiomed.2005.06.011.
Free Radic Biol Med. 2005.
PMID: 16214035
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Differential nitros(yl)ation of blood and tissue constituents during glyceryl trinitrate biotransformation in vivo.
Janero DR, Bryan NS, Saijo F, Dhawan V, Schwalb DJ, Warren MC, Feelisch M.
Janero DR, et al. Among authors: schwalb dj.
Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16958-63. doi: 10.1073/pnas.0406075101. Epub 2004 Nov 18.
Proc Natl Acad Sci U S A. 2004.
PMID: 15550545
Free PMC article.
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NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor.
Ellis JL, Augustyniak ME, Cochran ED, Earl RA, Garvey DS, Gordon LJ, Janero DR, Khanapure SP, Letts LG, Melim TL, Murty MG, Schwalb DJ, Shumway MJ, Selig WM, Trocha AM, Young DV, Zemtseva IS.
Ellis JL, et al. Among authors: schwalb dj.
Inflammopharmacology. 2005;12(5-6):521-34. doi: 10.1163/156856005774382661.
Inflammopharmacology. 2005.
PMID: 16259719
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3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors.
Ranatunge RR, Earl RA, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Schwalb DJ, Young DV, Zemtseva IS.
Ranatunge RR, et al. Among authors: schwalb dj.
Bioorg Med Chem Lett. 2004 Dec 20;14(24):6049-52. doi: 10.1016/j.bmcl.2004.09.073.
Bioorg Med Chem Lett. 2004.
PMID: 15546727
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3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone as a potent and orally active cyclooxygenase-2 selective inhibitor: synthesis and biological evaluation.
Khanapure SP, Augustyniak ME, Earl RA, Garvey DS, Letts LG, Martino AM, Murty MG, Schwalb DJ, Shumway MJ, Trocha AM, Young DV, Zemtseva IS, Janero DR.
Khanapure SP, et al. Among authors: schwalb dj.
J Med Chem. 2005 Jun 2;48(11):3930-4. doi: 10.1021/jm0582064.
J Med Chem. 2005.
PMID: 15916445
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