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A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients.
Kim KH, Ryan MJ, Estep JE, Miniard BM, Rudge TL, Peggins JO, Broadt TL, Wang M, Preuss MA, Siegal GP, Hemminki A, Harris RD, Aurigemma R, Curiel DT, Alvarez RD. Kim KH, et al. Among authors: estep je. Hum Gene Ther. 2011 Jul;22(7):821-8. doi: 10.1089/hum.2010.180. Epub 2011 Mar 23. Hum Gene Ther. 2011. PMID: 21171861 Free PMC article.
A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques.
Quinn CP, Sabourin CL, Niemuth NA, Li H, Semenova VA, Rudge TL, Mayfield HJ, Schiffer J, Mittler RS, Ibegbu CC, Wrammert J, Ahmed R, Brys AM, Hunt RE, Levesque D, Estep JE, Barnewall RE, Robinson DM, Plikaytis BD, Marano N; AVRP Laboratory Working Group. Quinn CP, et al. Among authors: estep je. Clin Vaccine Immunol. 2012 Nov;19(11):1730-45. doi: 10.1128/CVI.00324-12. Epub 2012 Aug 29. Clin Vaccine Immunol. 2012. PMID: 22933399 Free PMC article.
Genetic immunization against anthrax.
Galloway D, Liner A, Legutki J, Mateczun A, Barnewall R, Estep J. Galloway D, et al. Vaccine. 2004 Apr 16;22(13-14):1604-8. doi: 10.1016/j.vaccine.2003.09.043. Vaccine. 2004. PMID: 15068841
A critical role for CD8 T cells in a nonhuman primate model of tuberculosis.
Chen CY, Huang D, Wang RC, Shen L, Zeng G, Yao S, Shen Y, Halliday L, Fortman J, McAllister M, Estep J, Hunt R, Vasconcelos D, Du G, Porcelli SA, Larsen MH, Jacobs WR Jr, Haynes BF, Letvin NL, Chen ZW. Chen CY, et al. PLoS Pathog. 2009 Apr;5(4):e1000392. doi: 10.1371/journal.ppat.1000392. Epub 2009 Apr 17. PLoS Pathog. 2009. PMID: 19381260 Free PMC article.
Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.
Qiu L, Huang D, Chen CY, Wang R, Shen L, Shen Y, Hunt R, Estep J, Haynes BF, Jacobs WR Jr, Letvin N, Du G, Chen ZW. Qiu L, et al. J Infect Dis. 2008 Nov 15;198(10):1514-9. doi: 10.1086/592448. J Infect Dis. 2008. PMID: 18811584 Free PMC article.
23 results