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Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties.
J Biol Chem. 2021 Aug;297(2):100951. doi: 10.1016/j.jbc.2021.100951. Epub 2021 Jul 10.
J Biol Chem. 2021.
PMID: 34252458
Free PMC article.
Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.
Giovinazzo JA, Thomson RP, Khalizova N, Zager PJ, Malani N, Rodriguez-Boulan E, Raper J, Schreiner R.
Giovinazzo JA, et al.
Elife. 2020 May 19;9:e51185. doi: 10.7554/eLife.51185.
Elife. 2020.
PMID: 32427098
Free PMC article.
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BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins.
Heneghan JF, Vandorpe DH, Shmukler BE, Giovinazzo JA, Raper J, Friedman DJ, Pollak MR, Alper SL.
Heneghan JF, et al. Among authors: giovinazzo ja.
Am J Physiol Cell Physiol. 2015 Sep 1;309(5):C332-47. doi: 10.1152/ajpcell.00142.2015. Epub 2015 Jun 24.
Am J Physiol Cell Physiol. 2015.
PMID: 26108665
Free PMC article.
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Multi-tier regulation of the streptomycete morphogenetic peptide SapB.
Gaskell AA, Giovinazzo JA, Fonte V, Willey JM.
Gaskell AA, et al. Among authors: giovinazzo ja.
Mol Microbiol. 2012 May;84(3):501-15. doi: 10.1111/j.1365-2958.2012.08041.x. Epub 2012 Apr 9.
Mol Microbiol. 2012.
PMID: 22486809
Free article.
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