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ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.
Metukuri MR, Zhang P, Basantani MK, Chin C, Stamateris RE, Alonso LC, Takane KK, Gramignoli R, Strom SC, O'Doherty RM, Stewart AF, Vasavada RC, Garcia-Ocaña A, Scott DK. Metukuri MR, et al. Among authors: alonso lc. Diabetes. 2012 Aug;61(8):2004-15. doi: 10.2337/db11-0802. Epub 2012 May 14. Diabetes. 2012. PMID: 22586588 Free PMC article.
Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.
Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP, Stewart AF, Garcia-Ocaña A, Alonso LC. Levitt HE, et al. Among authors: alonso lc. Diabetologia. 2011 Mar;54(3):572-82. doi: 10.1007/s00125-010-1919-1. Epub 2010 Oct 9. Diabetologia. 2011. PMID: 20936253 Free PMC article.
Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A. Velazquez-Garcia S, et al. Among authors: alonso lc. Diabetes. 2011 Oct;60(10):2546-59. doi: 10.2337/db10-1783. Epub 2011 Sep 12. Diabetes. 2011. PMID: 21911744 Free PMC article.
74 results