Swan GE - Search Results

1

The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex.

Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. Zhu AZ, et al. Among authors: swan ge. Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):708-18. doi: 10.1158/1055-9965.EPI-12-1234-T. Epub 2013 Jan 31. Cancer Epidemiol Biomarkers Prev. 2013. PMID: 23371292 Free PMC article.

2

Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics.

Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. Al Koudsi N, et al. Among authors: swan ge. Eur J Clin Pharmacol. 2006 Jun;62(6):481-4. doi: 10.1007/s00228-006-0113-3. Epub 2006 Apr 28. Eur J Clin Pharmacol. 2006. PMID: 16758265

3

Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial.

Lerman C, Schnoll RA, Hawk LW Jr, Cinciripini P, George TP, Wileyto EP, Swan GE, Benowitz NL, Heitjan DF, Tyndale RF; PGRN-PNAT Research Group. Lerman C, et al. Among authors: swan ge. Lancet Respir Med. 2015 Feb;3(2):131-138. doi: 10.1016/S2213-2600(14)70294-2. Epub 2015 Jan 12. Lancet Respir Med. 2015. PMID: 25588294 Free PMC article. Clinical Trial.

4

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption.

Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE; Transdisciplinary Research in Cancer of the Lung Research Team. Bergen AW, et al. Among authors: swan ge. PLoS One. 2015 Jul 1;10(7):e0126113. doi: 10.1371/journal.pone.0126113. eCollection 2015. PLoS One. 2015. PMID: 26132489 Free PMC article.

5

Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.

Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF. Mwenifumbo JC, et al. Among authors: swan ge. Clin Pharmacol Ther. 2008 Jan;83(1):115-21. doi: 10.1038/sj.clpt.6100246. Epub 2007 May 23. Clin Pharmacol Ther. 2008. PMID: 17522595 Free PMC article. Clinical Trial.

6

Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence.

Swan GE, Benowitz NL, Lessov CN, Jacob P 3rd, Tyndale RF, Wilhelmsen K. Swan GE, et al. Pharmacogenet Genomics. 2005 Feb;15(2):115-25. doi: 10.1097/01213011-200502000-00007. Pharmacogenet Genomics. 2005. PMID: 15861035

7

Female sex and oral contraceptive use accelerate nicotine metabolism.

Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P 3rd. Benowitz NL, et al. Among authors: swan ge. Clin Pharmacol Ther. 2006 May;79(5):480-8. doi: 10.1016/j.clpt.2006.01.008. Clin Pharmacol Ther. 2006. PMID: 16678549 Clinical Trial.

8

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

Benowitz NL, Swan GE, Jacob P 3rd, Lessov-Schlaggar CN, Tyndale RF. Benowitz NL, et al. Among authors: swan ge. Clin Pharmacol Ther. 2006 Nov;80(5):457-67. doi: 10.1016/j.clpt.2006.08.011. Clin Pharmacol Ther. 2006. PMID: 17112802 Clinical Trial.

9

Genetic and environmental sources of variation in heart rate response to infused nicotine in twins.

Swan GE, Lessov-Schlaggar CN, Krasnow RE, Wilhelmsen KC, Jacob P 3rd, Benowitz NL. Swan GE, et al. Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1057-64. doi: 10.1158/1055-9965.EPI-06-1093. Cancer Epidemiol Biomarkers Prev. 2007. PMID: 17548663 Clinical Trial.

10

Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism.

Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P 3rd, Tyndale RF, Swan GE, Benowitz NL. Ring HZ, et al. Among authors: swan ge. Pharmacogenet Genomics. 2007 Dec;17(12):1007-15. doi: 10.1097/01.fpc.0000220560.59972.33. Pharmacogenet Genomics. 2007. PMID: 18004205

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