Freire E - Search Results

1

Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis.

Wang S, Ketcham SA, Schön A, Goodman B, Wang Y, Yates J 3rd, Freire E, Schroer TA, Zheng Y. Wang S, et al. Among authors: freire e. Mol Biol Cell. 2013 Nov;24(22):3522-33. doi: 10.1091/mbc.E13-05-0283. Epub 2013 Sep 11. Mol Biol Cell. 2013. PMID: 24025714 Free PMC article.

2

Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1.

Schön A, Freire E. Schön A, et al. Among authors: freire e. Biochemistry. 1989 Jun 13;28(12):5019-24. doi: 10.1021/bi00438a017. Biochemistry. 1989. PMID: 2765522

Previously, we have shown that the association of cholera toxin to ganglioside GM1 enhances the cooperative interactions between subunits in the B-subunit pentamer [Goins, B., & Freire, E. (1988) Biochemistry 27, 2046-2052]. New experiments presented in this pap …

Previously, we have shown that the association of cholera toxin to ganglioside GM1 enhances the cooperative interactions between subunits in …

3

The binding of HIV-1 protease inhibitors to human serum proteins.

Schön A, del Mar Ingaramo M, Freire E. Schön A, et al. Among authors: freire e. Biophys Chem. 2003 Sep;105(2-3):221-30. doi: 10.1016/s0301-4622(03)00071-1. Biophys Chem. 2003. PMID: 14499894

4

Multidrug resistance to HIV-1 protease inhibition requires cooperative coupling between distal mutations.

Ohtaka H, Schön A, Freire E. Ohtaka H, et al. Among authors: freire e. Biochemistry. 2003 Nov 25;42(46):13659-66. doi: 10.1021/bi0350405. Biochemistry. 2003. PMID: 14622012

5

Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.

Velazquez-Campoy A, Muzammil S, Ohtaka H, Schön A, Vega S, Freire E. Velazquez-Campoy A, et al. Among authors: freire e. Curr Drug Targets Infect Disord. 2003 Dec;3(4):311-28. doi: 10.2174/1568005033481051. Curr Drug Targets Infect Disord. 2003. PMID: 14754432 Review.

6

Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.

Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Leavitt SA, et al. Among authors: freire e. Curr Protein Pept Sci. 2004 Feb;5(1):1-8. doi: 10.2174/1389203043486955. Curr Protein Pept Sci. 2004. PMID: 14965316 Review.

7

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.

Ohtaka H, Muzammil S, Schön A, Velazquez-Campoy A, Vega S, Freire E. Ohtaka H, et al. Among authors: freire e. Int J Biochem Cell Biol. 2004 Sep;36(9):1787-99. doi: 10.1016/j.biocel.2004.02.021. Int J Biochem Cell Biol. 2004. PMID: 15183345 Review.

8

Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis.

Pancera M, Lebowitz J, Schön A, Zhu P, Freire E, Kwong PD, Roux KH, Sodroski J, Wyatt R. Pancera M, et al. Among authors: freire e. J Virol. 2005 Aug;79(15):9954-69. doi: 10.1128/JVI.79.15.9954-9969.2005. J Virol. 2005. PMID: 16014956 Free PMC article.

9

Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins.

Aguilar RC, Longhi SA, Shaw JD, Yeh LY, Kim S, Schön A, Freire E, Hsu A, McCormick WK, Watson HA, Wendland B. Aguilar RC, et al. Among authors: freire e. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4116-21. doi: 10.1073/pnas.0510513103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537494 Free PMC article.

10

Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.

Schön A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB 3rd, Sodroski J, Freire E. Schön A, et al. Among authors: freire e. Biochemistry. 2006 Sep 12;45(36):10973-80. doi: 10.1021/bi061193r. Biochemistry. 2006. PMID: 16953583 Free PMC article.

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