Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

306 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
A hormone-DNA repair circuit governs the response to genotoxic insult.
Goodwin JF, Schiewer MJ, Dean JL, Schrecengost RS, de Leeuw R, Han S, Ma T, Den RB, Dicker AP, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: de leeuw r. Cancer Discov. 2013 Nov;3(11):1254-71. doi: 10.1158/2159-8290.CD-13-0108. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027197 Free PMC article.
Targeting cell cycle and hormone receptor pathways in cancer.
Comstock CE, Augello MA, Goodwin JF, de Leeuw R, Schiewer MJ, Ostrander WF Jr, Burkhart RA, McClendon AK, McCue PA, Trabulsi EJ, Lallas CD, Gomella LG, Centenera MM, Brody JR, Butler LM, Tilley WD, Knudsen KE. Comstock CE, et al. Among authors: de leeuw r. Oncogene. 2013 Nov 28;32(48):5481-91. doi: 10.1038/onc.2013.83. Epub 2013 May 27. Oncogene. 2013. PMID: 23708653 Free PMC article.
MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer.
de Leeuw R, McNair C, Schiewer MJ, Neupane NP, Brand LJ, Augello MA, Li Z, Cheng LC, Yoshida A, Courtney SM, Hazard ES, Hardiman G, Hussain MH, Diehl JA, Drake JM, Kelly WK, Knudsen KE. de Leeuw R, et al. Clin Cancer Res. 2018 Sep 1;24(17):4201-4214. doi: 10.1158/1078-0432.CCR-18-0410. Epub 2018 May 8. Clin Cancer Res. 2018. PMID: 29739788 Free PMC article.
PARP-1 regulates DNA repair factor availability.
Schiewer MJ, Mandigo AC, Gordon N, Huang F, Gaur S, de Leeuw R, Zhao SG, Evans J, Han S, Parsons T, Birbe R, McCue P, McNair C, Chand SN, Cendon-Florez Y, Gallagher P, McCann JJ, Poudel Neupane N, Shafi AA, Dylgjeri E, Brand LJ, Visakorpi T, Raj GV, Lallas CD, Trabulsi EJ, Gomella LG, Dicker AP, Kelly WK, Leiby BE, Knudsen B, Feng FY, Knudsen KE. Schiewer MJ, et al. Among authors: de leeuw r. EMBO Mol Med. 2018 Dec;10(12):e8816. doi: 10.15252/emmm.201708816. EMBO Mol Med. 2018. PMID: 30467127 Free PMC article.
Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response.
Shafi AA, Schiewer MJ, de Leeuw R, Dylgjeri E, McCue PA, Shah N, Gomella LG, Lallas CD, Trabulsi EJ, Centenera MM, Hickey TE, Butler LM, Raj G, Tilley WD, Cukierman E, Knudsen KE. Shafi AA, et al. Among authors: de leeuw r. Eur Urol Oncol. 2018 Sep;1(4):325-337. doi: 10.1016/j.euo.2018.04.019. Epub 2018 Jun 6. Eur Urol Oncol. 2018. PMID: 30467556 Free PMC article.
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies.
Dylgjeri E, McNair C, Goodwin JF, Raymon HK, McCue PA, Shafi AA, Leiby BE, de Leeuw R, Kothari V, McCann JJ, Mandigo AC, Chand SN, Schiewer MJ, Brand LJ, Vasilevskaya I, Gordon N, Laufer TS, Gomella LG, Lallas CD, Trabulsi EJ, Feng FY, Filvaroff EH, Hege K, Rathkopf D, Knudsen KE. Dylgjeri E, et al. Among authors: de leeuw r. Clin Cancer Res. 2019 Sep 15;25(18):5623-5637. doi: 10.1158/1078-0432.CCR-18-2207. Epub 2019 Jul 2. Clin Cancer Res. 2019. PMID: 31266833 Free PMC article.
SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.
Yoshida A, Bu Y, Qie S, Wrangle J, Camp ER, Hazard ES, Hardiman G, de Leeuw R, Knudsen KE, Diehl JA. Yoshida A, et al. Among authors: de leeuw r. Sci Adv. 2019 Sep 18;5(9):eaax6352. doi: 10.1126/sciadv.aax6352. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31555743 Free PMC article.
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes.
McCann JJ, Vasilevskaya IA, McNair C, Gallagher P, Neupane NP, de Leeuw R, Shafi AA, Dylgjeri E, Mandigo AC, Schiewer MJ, Knudsen KE. McCann JJ, et al. Among authors: de leeuw r. Oncogene. 2022 Jan;41(3):444-458. doi: 10.1038/s41388-021-01903-5. Epub 2021 Nov 12. Oncogene. 2022. PMID: 34773073 Free PMC article.
306 results