Margittai M - Search Results

1

Single mutations in tau modulate the populations of fibril conformers through seed selection.

Meyer V, Dinkel PD, Luo Y, Yu X, Wei G, Zheng J, Eaton GR, Ma B, Nussinov R, Eaton SS, Margittai M. Meyer V, et al. Among authors: margittai m. Angew Chem Int Ed Engl. 2014 Feb 3;53(6):1590-3. doi: 10.1002/anie.201308473. Epub 2014 Jan 22. Angew Chem Int Ed Engl. 2014. PMID: 24453187 Free PMC article.

2

Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy.

Margittai M, Langen R. Margittai M, et al. Q Rev Biophys. 2008 Aug-Nov;41(3-4):265-97. doi: 10.1017/S0033583508004733. Q Rev Biophys. 2008. PMID: 19079806 Review.

3

Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease.

Siddiqua A, Margittai M. Siddiqua A, et al. Among authors: margittai m. J Biol Chem. 2010 Nov 26;285(48):37920-6. doi: 10.1074/jbc.M110.185728. Epub 2010 Oct 4. J Biol Chem. 2010. PMID: 20921227 Free PMC article.

4

Variations in filament conformation dictate seeding barrier between three- and four-repeat tau.

Dinkel PD, Siddiqua A, Huynh H, Shah M, Margittai M. Dinkel PD, et al. Among authors: margittai m. Biochemistry. 2011 May 24;50(20):4330-6. doi: 10.1021/bi2004685. Epub 2011 May 2. Biochemistry. 2011. PMID: 21510682

5

Cross-seeding and conformational selection between three- and four-repeat human Tau proteins.

Yu X, Luo Y, Dinkel P, Zheng J, Wei G, Margittai M, Nussinov R, Ma B. Yu X, et al. Among authors: margittai m. J Biol Chem. 2012 Apr 27;287(18):14950-9. doi: 10.1074/jbc.M112.340794. Epub 2012 Mar 5. J Biol Chem. 2012. PMID: 22393063 Free PMC article.

6

Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau.

Siddiqua A, Luo Y, Meyer V, Swanson MA, Yu X, Wei G, Zheng J, Eaton GR, Ma B, Nussinov R, Eaton SS, Margittai M. Siddiqua A, et al. Among authors: margittai m. J Am Chem Soc. 2012 Jun 20;134(24):10271-8. doi: 10.1021/ja303498q. Epub 2012 Jun 12. J Am Chem Soc. 2012. PMID: 22656332 Free PMC article.

7

Molecular insights into the reversible formation of tau protein fibrils.

Luo Y, Dinkel P, Yu X, Margittai M, Zheng J, Nussinov R, Wei G, Ma B. Luo Y, et al. Among authors: margittai m. Chem Commun (Camb). 2013 May 4;49(34):3582-4. doi: 10.1039/c3cc00241a. Chem Commun (Camb). 2013. PMID: 23527380 Free PMC article.

8

Amplification of Tau fibrils from minute quantities of seeds.

Meyer V, Dinkel PD, Rickman Hager E, Margittai M. Meyer V, et al. Among authors: margittai m. Biochemistry. 2014 Sep 16;53(36):5804-9. doi: 10.1021/bi501050g. Epub 2014 Aug 29. Biochemistry. 2014. PMID: 25153692 Free PMC article.

9

RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth.

Dinkel PD, Holden MR, Matin N, Margittai M. Dinkel PD, et al. Among authors: margittai m. Biochemistry. 2015 Aug 4;54(30):4731-40. doi: 10.1021/acs.biochem.5b00453. Epub 2015 Jul 27. Biochemistry. 2015. PMID: 26177386 Free PMC article.

10

Spin Labeling and Characterization of Tau Fibrils Using Electron Paramagnetic Resonance (EPR).

Meyer V, Margittai M. Meyer V, et al. Among authors: margittai m. Methods Mol Biol. 2016;1345:185-99. doi: 10.1007/978-1-4939-2978-8_12. Methods Mol Biol. 2016. PMID: 26453213

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