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Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Hewitt WM, Lountos GT, Zlotkowski K, Dahlhauser SD, Saunders LB, Needle D, Tropea JE, Zhan C, Wei G, Ma B, Nussinov R, Waugh DS, Schneekloth JS Jr. Hewitt WM, et al. Among authors: wei g. Angew Chem Int Ed Engl. 2016 May 4;55(19):5703-7. doi: 10.1002/anie.201511351. Epub 2016 Apr 1. Angew Chem Int Ed Engl. 2016. PMID: 27038327 Free PMC article.
Conformational stability and dynamics of the cancer-associated isoform Δ133p53β are modulated by p53 peptides and p53-specific DNA.
Lei J, Qi R, Tang Y, Wang W, Wei G, Nussinov R, Ma B. Lei J, et al. Among authors: wei g. FASEB J. 2019 Mar;33(3):4225-4235. doi: 10.1096/fj.201801973R. Epub 2018 Dec 12. FASEB J. 2019. PMID: 30540922 Free PMC article.
This study provides physicochemical insight into delta133p53beta, delta133p53beta-DNA complexes, delta133p53beta's pathologic mechanism, and peptide-based inhibitor design against p53-related cancers.-Lei, J., Qi, R., Tang, Y., Wang, W., Wei, G., Nussinov, R., Ma, B …
This study provides physicochemical insight into delta133p53beta, delta133p53beta-DNA complexes, delta133p53beta's pathologic mechanism, and …
4,740 results