Wang S - Search Results

1

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.

Asangani IA, Dommeti VL, Wang X, Malik R, Cieslik M, Yang R, Escara-Wilke J, Wilder-Romans K, Dhanireddy S, Engelke C, Iyer MK, Jing X, Wu YM, Cao X, Qin ZS, Wang S, Feng FY, Chinnaiyan AM. Asangani IA, et al. Among authors: wang x, wang s. Nature. 2014 Jun 12;510(7504):278-82. doi: 10.1038/nature13229. Epub 2014 Apr 23. Nature. 2014. PMID: 24759320 Free PMC article.

2

Targeting the MDM2-p53 interaction for cancer therapy.

Shangary S, Wang S. Shangary S, et al. Among authors: wang s. Clin Cancer Res. 2008 Sep 1;14(17):5318-24. doi: 10.1158/1078-0432.CCR-07-5136. Clin Cancer Res. 2008. PMID: 18765522 Free PMC article. Review.

3

AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.

McGregor N, Patel L, Craig M, Weidner S, Wang S, Pienta KJ. McGregor N, et al. Among authors: wang s. J Cell Biochem. 2010 Aug 1;110(5):1187-94. doi: 10.1002/jcb.22633. J Cell Biochem. 2010. PMID: 20589722 Free article.

4

Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.

Lu J, McEachern D, Sun H, Bai L, Peng Y, Qiu S, Miller R, Liao J, Yi H, Liu M, Bellail A, Hao C, Sun SY, Ting AT, Wang S. Lu J, et al. Among authors: wang s. Mol Cancer Ther. 2011 May;10(5):902-14. doi: 10.1158/1535-7163.MCT-10-0864. Epub 2011 Mar 3. Mol Cancer Ther. 2011. PMID: 21372226 Free PMC article.

5

The making of I-BET762, a BET bromodomain inhibitor now in clinical development.

Zhao Y, Yang CY, Wang S. Zhao Y, et al. Among authors: wang s. J Med Chem. 2013 Oct 10;56(19):7498-500. doi: 10.1021/jm4014407. Epub 2013 Sep 25. J Med Chem. 2013. PMID: 24107192

6

Targeting apoptosis pathways for new cancer therapeutics.

Bai L, Wang S. Bai L, et al. Among authors: wang s. Annu Rev Med. 2014;65:139-55. doi: 10.1146/annurev-med-010713-141310. Epub 2013 Nov 4. Annu Rev Med. 2014. PMID: 24188661 Review.

7

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: wang s. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.

8

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.

Zhao Y, Aguilar A, Bernard D, Wang S. Zhao Y, et al. Among authors: wang s. J Med Chem. 2015 Feb 12;58(3):1038-52. doi: 10.1021/jm501092z. Epub 2014 Nov 14. J Med Chem. 2015. PMID: 25396320 Free PMC article. Review.

9

BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice.

Sun Y, Wang Y, Toubai T, Oravecz-Wilson K, Liu C, Mathewson N, Wu J, Rossi C, Cummings E, Wu D, Wang S, Reddy P. Sun Y, et al. Among authors: wang y, wang s. Blood. 2015 Apr 23;125(17):2724-8. doi: 10.1182/blood-2014-08-598037. Epub 2015 Mar 16. Blood. 2015. PMID: 25778533 Free PMC article.

10

Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors.

Ran X, Zhao Y, Liu L, Bai L, Yang CY, Zhou B, Meagher JL, Chinnaswamy K, Stuckey JA, Wang S. Ran X, et al. Among authors: wang s. J Med Chem. 2015 Jun 25;58(12):4927-39. doi: 10.1021/acs.jmedchem.5b00613. Epub 2015 Jun 16. J Med Chem. 2015. PMID: 26080064 Free PMC article.

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