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Molecular mechanism of regulation of the atypical protein kinase C by N-terminal domains and an allosteric small compound.
Zhang H, Neimanis S, Lopez-Garcia LA, Arencibia JM, Amon S, Stroba A, Zeuzem S, Proschak E, Stark H, Bauer AF, Busschots K, Jørgensen TJ, Engel M, Schulze JO, Biondi RM. Zhang H, et al. Among authors: stroba a. Chem Biol. 2014 Jun 19;21(6):754-65. doi: 10.1016/j.chembiol.2014.04.007. Epub 2014 May 15. Chem Biol. 2014. PMID: 24836908
Allosteric activation of the protein kinase PDK1 with low molecular weight compounds.
Engel M, Hindie V, Lopez-Garcia LA, Stroba A, Schaeffer F, Adrian I, Imig J, Idrissova L, Nastainczyk W, Zeuzem S, Alzari PM, Hartmann RW, Piiper A, Biondi RM. Engel M, et al. Among authors: stroba a. EMBO J. 2006 Nov 29;25(23):5469-80. doi: 10.1038/sj.emboj.7601416. Epub 2006 Nov 16. EMBO J. 2006. PMID: 17110931 Free PMC article.