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Transcriptome changes affecting Hedgehog and cytokine signalling in the umbilical cord: implications for disease risk.
Stünkel W, Pan H, Chew SB, Tng E, Tan JH, Chen L, Joseph R, Cheong CY, Ong ML, Lee YS, Chong YS, Saw SM, Meaney MJ, Kwek K, Sheppard AM, Gluckman PD; GUSTO Study Group; Holbrook JD. Stünkel W, et al. Among authors: holbrook jd. PLoS One. 2012;7(7):e39744. doi: 10.1371/journal.pone.0039744. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22808055 Free PMC article.
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome.
Lin X, Lim IY, Wu Y, Teh AL, Chen L, Aris IM, Soh SE, Tint MT, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Holbrook JD, Lee YS, Gluckman PD, Karnani N; GUSTO study group. Lin X, et al. Among authors: holbrook jd. BMC Med. 2017 Mar 7;15(1):50. doi: 10.1186/s12916-017-0800-1. BMC Med. 2017. PMID: 28264723 Free PMC article.
Choice of surrogate tissue influences neonatal EWAS findings.
Lin X, Teh AL, Chen L, Lim IY, Tan PF, MacIsaac JL, Morin AM, Yap F, Tan KH, Saw SM, Lee YS, Holbrook JD, Godfrey KM, Meaney MJ, Kobor MS, Chong YS, Gluckman PD, Karnani N. Lin X, et al. Among authors: holbrook jd. BMC Med. 2017 Dec 5;15(1):211. doi: 10.1186/s12916-017-0970-x. BMC Med. 2017. PMID: 29202839 Free PMC article.
HIF3A association with adiposity: the story begins before birth.
Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group. Pan H, et al. Among authors: holbrook jd. Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26. Epigenomics. 2015. PMID: 26011824 Free PMC article.
Neonatal amygdalae and hippocampi are influenced by genotype and prenatal environment, and reflected in the neonatal DNA methylome.
Ong ML, Tuan TA, Poh J, Teh AL, Chen L, Pan H, MacIsaac JL, Kobor MS, Chong YS, Kwek K, Saw SM, Godfrey KM, Gluckman PD, Fortier MV, Karnani N, Meaney MJ, Qiu A, Holbrook JD. Ong ML, et al. Among authors: holbrook jd. Genes Brain Behav. 2019 Sep;18(7):e12576. doi: 10.1111/gbb.12576. Epub 2019 May 15. Genes Brain Behav. 2019. PMID: 31020763 Free article.
109 results