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MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ. Cheng CJ, et al. Among authors: engelman dm. Nature. 2015 Feb 5;518(7537):107-10. doi: 10.1038/nature13905. Epub 2014 Nov 17. Nature. 2015. PMID: 25409146 Free PMC article.
OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer.
Svoronos AA, Engelman DM, Slack FJ. Svoronos AA, et al. Among authors: engelman dm. Cancer Res. 2016 Jul 1;76(13):3666-70. doi: 10.1158/0008-5472.CAN-16-0359. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325641 Free PMC article. Review.
Membrane physical properties influence transmembrane helix formation.
Barrera FN, Fendos J, Engelman DM. Barrera FN, et al. Among authors: engelman dm. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14422-7. doi: 10.1073/pnas.1212665109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908237 Free PMC article.
Aspartate embedding depth affects pHLIP's insertion pKa.
Fendos J, Barrera FN, Engelman DM. Fendos J, et al. Among authors: engelman dm. Biochemistry. 2013 Jul 9;52(27):4595-604. doi: 10.1021/bi400252k. Epub 2013 Jun 27. Biochemistry. 2013. PMID: 23721379 Free PMC article.
Roles of carboxyl groups in the transmembrane insertion of peptides.
Barrera FN, Weerakkody D, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM. Barrera FN, et al. Among authors: engelman dm. J Mol Biol. 2011 Oct 21;413(2):359-71. doi: 10.1016/j.jmb.2011.08.010. Epub 2011 Aug 23. J Mol Biol. 2011. PMID: 21888917 Free PMC article.
241 results