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Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.
Ewald DA, Noda S, Oliva M, Litman T, Nakajima S, Li X, Xu H, Workman CT, Scheipers P, Svitacheva N, Labuda T, Krueger JG, Suárez-Fariñas M, Kabashima K, Guttman-Yassky E. Ewald DA, et al. Among authors: litman t. J Allergy Clin Immunol. 2017 Feb;139(2):562-571. doi: 10.1016/j.jaci.2016.08.029. Epub 2016 Oct 1. J Allergy Clin Immunol. 2017. PMID: 27702671
IκBζ is a key player in the antipsoriatic effects of secukinumab.
Bertelsen T, Ljungberg C, Litman T, Huppertz C, Hennze R, Rønholt K, Iversen L, Johansen C. Bertelsen T, et al. Among authors: litman t. J Allergy Clin Immunol. 2020 Jan;145(1):379-390. doi: 10.1016/j.jaci.2019.09.029. Epub 2019 Oct 14. J Allergy Clin Immunol. 2020. PMID: 31622687 Free article. Clinical Trial.
Elevated NK-cell transcriptional signature and dysbalance of resting and activated NK cells in atopic dermatitis.
Möbus L, Rodriguez E, Harder I, Schwarz A, Wehkamp U, Stölzl D, Boraczynski N, Gerdes S, Litman T, Kleinheinz A, Abraham S, Heratizadeh A, Handrick C, Haufe E, Schmitt J, Werfel T, Weidinger S; TREATgermany Study Group. Möbus L, et al. Among authors: litman t. J Allergy Clin Immunol. 2021 May;147(5):1959-1965.e2. doi: 10.1016/j.jaci.2020.11.022. Epub 2020 Dec 31. J Allergy Clin Immunol. 2021. PMID: 33390269
Skin Barrier and Inflammation Genes Associated with Atopic Dermatitis are Regulated by Interleukin-13 and Modulated by Tralokinumab In vitro.
Tollenaere MAX, Litman T, Moebus L, Rodriguez E, Stölzl D, Drerup K, Werfel T, Schmitt J, Norsgaard H, Weidinger S. Tollenaere MAX, et al. Among authors: litman t. Acta Derm Venereol. 2021 Apr 29;101(4):adv00447. doi: 10.2340/00015555-3810. Acta Derm Venereol. 2021. PMID: 33899112 Free PMC article. No abstract available.
C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin.
Dainichi T, Nakano Y, Doi H, Nakamizo S, Nakajima S, Matsumoto R, Farkas T, Wong PM, Narang V, Moreno Traspas R, Kawakami E, Guttman-Yassky E, Dreesen O, Litman T, Reversade B, Kabashima K. Dainichi T, et al. Among authors: litman t. Front Immunol. 2022 Feb 22;13:825032. doi: 10.3389/fimmu.2022.825032. eCollection 2022. Front Immunol. 2022. PMID: 35273606 Free PMC article.
158 results