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RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.
Suárez-Fariñas M, Ungar B, Correa da Rosa J, Ewald DA, Rozenblit M, Gonzalez J, Xu H, Zheng X, Peng X, Estrada YD, Dillon SR, Krueger JG, Guttman-Yassky E. Suárez-Fariñas M, et al. Among authors: dillon sr. J Allergy Clin Immunol. 2015 May;135(5):1218-27. doi: 10.1016/j.jaci.2015.03.003. Epub 2015 Mar 31. J Allergy Clin Immunol. 2015. PMID: 25840722
The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves.
Feld M, Garcia R, Buddenkotte J, Katayama S, Lewis K, Muirhead G, Hevezi P, Plesser K, Schrumpf H, Krjutskov K, Sergeeva O, Müller HW, Tsoka S, Kere J, Dillon SR, Steinhoff M, Homey B. Feld M, et al. Among authors: dillon sr. J Allergy Clin Immunol. 2016 Aug;138(2):500-508.e24. doi: 10.1016/j.jaci.2016.02.020. Epub 2016 Apr 6. J Allergy Clin Immunol. 2016. PMID: 27212086
A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.
Cevikbas F, Wang X, Akiyama T, Kempkes C, Savinko T, Antal A, Kukova G, Buhl T, Ikoma A, Buddenkotte J, Soumelis V, Feld M, Alenius H, Dillon SR, Carstens E, Homey B, Basbaum A, Steinhoff M. Cevikbas F, et al. Among authors: dillon sr. J Allergy Clin Immunol. 2014 Feb;133(2):448-60. doi: 10.1016/j.jaci.2013.10.048. Epub 2013 Dec 25. J Allergy Clin Immunol. 2014. PMID: 24373353 Free PMC article.
Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.
Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA. Dillon SR, et al. Nat Immunol. 2004 Jul;5(7):752-60. doi: 10.1038/ni1084. Epub 2004 Jun 6. Nat Immunol. 2004. PMID: 15184896
IL-31 transgenic mice show reduced allergen-induced lung inflammation.
Neuper T, Neureiter D, Sarajlic M, Strandt H, Bauer R, Schwarz H, Suchanek P, Korotchenko E, Dillon SR, Hammerl P, Stoecklinger A, Weiss R, Horejs-Hoeck J. Neuper T, et al. Among authors: dillon sr. Eur J Immunol. 2021 Jan;51(1):191-196. doi: 10.1002/eji.202048547. Epub 2020 Jul 21. Eur J Immunol. 2021. PMID: 32648940 Free PMC article.
68 results