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Page 1
Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform.
Treweek S, Altman DG, Bower P, Campbell M, Chalmers I, Cotton S, Craig P, Crosby D, Davidson P, Devane D, Duley L, Dunn J, Elbourne D, Farrell B, Gamble C, Gillies K, Hood K, Lang T, Littleford R, Loudon K, McDonald A, McPherson G, Nelson A, Norrie J, Ramsay C, Sandercock P, Shanahan DR, Summerskill W, Sydes M, Williamson P, Clarke M. Treweek S, et al. Among authors: littleford r. Trials. 2015 Jun 5;16:261. doi: 10.1186/s13063-015-0776-0. Trials. 2015. PMID: 26044814 Free PMC article.
Trial Forge Guidance 1: what is a Study Within A Trial (SWAT)?
Treweek S, Bevan S, Bower P, Campbell M, Christie J, Clarke M, Collett C, Cotton S, Devane D, El Feky A, Flemyng E, Galvin S, Gardner H, Gillies K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, Sullivan F, Torgerson D, Tremain L, Westmore M, Williamson PR. Treweek S, et al. Among authors: littleford r. Trials. 2018 Feb 23;19(1):139. doi: 10.1186/s13063-018-2535-5. Trials. 2018. PMID: 29475444 Free PMC article.
Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed.
Treweek S, Bevan S, Bower P, Briel M, Campbell M, Christie J, Collett C, Cotton S, Devane D, El Feky A, Galvin S, Gardner H, Gillies K, Hood K, Jansen J, Littleford R, Parker A, Ramsay C, Restrup L, Sullivan F, Torgerson D, Tremain L, von Elm E, Westmore M, Williams H, Williamson PR, Clarke M. Treweek S, et al. Among authors: littleford r. Trials. 2020 Jan 7;21(1):33. doi: 10.1186/s13063-019-3980-5. Trials. 2020. PMID: 31910861 Free PMC article.
The effect of optimised patient information materials on recruitment in a lung cancer screening trial: an embedded randomised recruitment trial.
Parker A, Knapp P, Treweek S, Madhurasinghe V, Littleford R, Gallant S, Sullivan F, Schembri S, Rick J, Graffy J, Collier DJ, Eldridge S, Kennedy A, Bower P. Parker A, et al. Among authors: littleford r. Trials. 2018 Sep 18;19(1):503. doi: 10.1186/s13063-018-2896-9. Trials. 2018. PMID: 30227890 Free PMC article. Clinical Trial.
The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial.
Denholm JT, Davis J, Paterson D, Roberts J, Morpeth S, Snelling T, Zentner D, Rees M, O'Sullivan M, Price D, Bowen A, Tong SYC; ASCOT Investigator Group. Denholm JT, et al. Trials. 2020 Jul 14;21(1):646. doi: 10.1186/s13063-020-04576-9. Trials. 2020. PMID: 32665040 Free PMC article.
Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial.
Witham MD, Band MM, Littleford RC, Avenell A, Soiza RL, McMurdo ME, Sumukadas D, Ogston SA, Lamb EJ, Hampson G, McNamee P; BiCARB Study Group. Witham MD, et al. Trials. 2015 Aug 1;16:326. doi: 10.1186/s13063-015-0843-6. Trials. 2015. PMID: 26231610 Free PMC article. Clinical Trial.
Earlier diagnosis of lung cancer in a randomised trial of an autoantibody blood test followed by imaging.
Sullivan FM, Mair FS, Anderson W, Armory P, Briggs A, Chew C, Dorward A, Haughney J, Hogarth F, Kendrick D, Littleford R, McConnachie A, McCowan C, McMeekin N, Patel M, Rauchhaus P, Ritchie L, Robertson C, Robertson J, Robles-Zurita J, Sarvesvaran J, Sewell H, Sproule M, Taylor T, Tello A, Treweek S, Vedhara K, Schembri S; Early Diagnosis of Lung Cancer Scotland (ECLS) Team. Sullivan FM, et al. Among authors: littleford r. Eur Respir J. 2021 Jan 14;57(1):2000670. doi: 10.1183/13993003.00670-2020. Print 2021 Jan. Eur Respir J. 2021. PMID: 32732334 Free PMC article. Clinical Trial.
Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial.
Sullivan FM, Farmer E, Mair FS, Treweek S, Kendrick D, Jackson C, Robertson C, Briggs A, McCowan C, Bedford L, Young B, Vedhara K, Gallant S, Littleford R, Robertson J, Sewell H, Dorward A, Sarvesvaran J, Schembri S. Sullivan FM, et al. Among authors: littleford r. BMC Cancer. 2017 Mar 11;17(1):187. doi: 10.1186/s12885-017-3175-y. BMC Cancer. 2017. PMID: 28284200 Free PMC article. Clinical Trial.
Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales ("MERINO-3"): study protocol for a multicentre, open-label randomised non-inferiority trial.
Stewart AG, Harris PNA, Chatfield MD, Littleford R, Paterson DL. Stewart AG, et al. Among authors: littleford r. Trials. 2021 Apr 22;22(1):301. doi: 10.1186/s13063-021-05206-8. Trials. 2021. PMID: 33888139 Free PMC article.
58 results