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Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma.
Jain S, Stroopinsky D, Yin L, Rosenblatt J, Alam M, Bhargava P, Clark RA, Kupper TS, Palmer K, Coll MD, Rajabi H, Pyzer A, Bar-Natan M, Luptakova K, Arnason J, Joyce R, Kufe D, Avigan D. Jain S, et al. Blood. 2015 Jul 16;126(3):354-62. doi: 10.1182/blood-2015-02-628149. Epub 2015 Jun 5. Blood. 2015. PMID: 26048911 Free PMC article.
Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.
Bar-Natan M, Stroopinsky D, Luptakova K, Coll MD, Apel A, Rajabi H, Pyzer AR, Palmer K, Reagan MR, Nahas MR, Karp Leaf R, Jain S, Arnason J, Ghobrial IM, Anderson KC, Kufe D, Rosenblatt J, Avigan D. Bar-Natan M, et al. Br J Haematol. 2017 Mar;176(6):929-938. doi: 10.1111/bjh.14493. Epub 2017 Jan 20. Br J Haematol. 2017. PMID: 28107546 Free PMC article.
MUC1-C drives myeloid leukaemogenesis and resistance to treatment by a survivin-mediated mechanism.
Stroopinsky D, Rajabi H, Nahas M, Rosenblatt J, Rahimian M, Pyzer A, Tagde A, Kharbanda A, Jain S, Kufe T, Leaf RK, Anastasiadou E, Bar-Natan M, Orr S, Coll MD, Palmer K, Ephraim A, Cole L, Washington A, Kufe D, Avigan D. Stroopinsky D, et al. J Cell Mol Med. 2018 Aug;22(8):3887-3898. doi: 10.1111/jcmm.13662. Epub 2018 May 15. J Cell Mol Med. 2018. PMID: 29761849 Free PMC article.
MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs.
Pyzer AR, Stroopinsky D, Rosenblatt J, Anastasiadou E, Rajabi H, Washington A, Tagde A, Chu JH, Coll M, Jiao AL, Tsai LT, Tenen DE, Cole L, Palmer K, Ephraim A, Leaf RK, Nahas M, Apel A, Bar-Natan M, Jain S, McMasters M, Mendez L, Arnason J, Raby BA, Slack F, Kufe D, Avigan D. Pyzer AR, et al. Leukemia. 2017 Dec;31(12):2780-2790. doi: 10.1038/leu.2017.163. Epub 2017 May 30. Leukemia. 2017. PMID: 28555079 Free PMC article.
Immunotherapy for multiple myeloma.
Rosenblatt J, Bar-Natan M, Munshi NC, Avigan DE. Rosenblatt J, et al. Expert Rev Hematol. 2014 Feb;7(1):91-6. doi: 10.1586/17474086.2014.878226. Epub 2014 Jan 13. Expert Rev Hematol. 2014. PMID: 24417573 Review.
Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures.
Herrera A, Cheng A, Mimitou EP, Seffens A, George D, Bar-Natan M, Heguy A, Ruggles KV, Scher JU, Hymes K, Latkowski JA, Ødum N, Kadin ME, Ouyang Z, Geskin LJ, Smibert P, Buus TB, Koralov SB. Herrera A, et al. Among authors: bar natan m. Blood. 2021 Oct 21;138(16):1456-1464. doi: 10.1182/blood.2020009346. Blood. 2021. PMID: 34232982 Free PMC article.
Gene expression-based discovery of atovaquone as a STAT3 inhibitor and anticancer agent.
Xiang M, Kim H, Ho VT, Walker SR, Bar-Natan M, Anahtar M, Liu S, Toniolo PA, Kroll Y, Jones N, Giaccone ZT, Heppler LN, Ye DQ, Marineau JJ, Shaw D, Bradner JE, Blonquist T, Neuberg D, Hetz C, Stone RM, Soiffer RJ, Frank DA. Xiang M, et al. Blood. 2016 Oct 6;128(14):1845-1853. doi: 10.1182/blood-2015-07-660506. Epub 2016 Aug 16. Blood. 2016. PMID: 27531676 Free PMC article.
NOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AML.
Adamia S, Bar-Natan M, Haibe-Kains B, Pilarski PM, Bach C, Pevzner S, Calimeri T, Avet-Loiseau H, Lode L, Verselis S, Fox EA, Galinsky I, Mathews S, Dagogo-Jack I, Wadleigh M, Steensma DP, Motyckova G, Deangelo DJ, Quackenbush J, Tenen DG, Stone RM, Griffin JD. Adamia S, et al. Blood. 2014 May 1;123(18):2816-25. doi: 10.1182/blood-2013-02-481507. Epub 2014 Feb 26. Blood. 2014. PMID: 24574459 Free PMC article.
TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
Bejar R, Lord A, Stevenson K, Bar-Natan M, Pérez-Ladaga A, Zaneveld J, Wang H, Caughey B, Stojanov P, Getz G, Garcia-Manero G, Kantarjian H, Chen R, Stone RM, Neuberg D, Steensma DP, Ebert BL. Bejar R, et al. Blood. 2014 Oct 23;124(17):2705-12. doi: 10.1182/blood-2014-06-582809. Epub 2014 Sep 15. Blood. 2014. PMID: 25224413 Free PMC article.
46 results