Ruzzene M - Search Results

1

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours.

Kalathur M, Toso A, Chen J, Revandkar A, Danzer-Baltzer C, Guccini I, Alajati A, Sarti M, Pinton S, Brambilla L, Di Mitri D, Carbone G, Garcia-Escudero R, Padova A, Magnoni L, Tarditi A, Maccari L, Malusa F, Kalathur RK, A Pinna L, Cozza G, Ruzzene M, Delaleu N, Catapano CV, Frew IJ, Alimonti A. Kalathur M, et al. Among authors: ruzzene m. Nat Commun. 2015 Jun 18;6:7227. doi: 10.1038/ncomms8227. Nat Commun. 2015. PMID: 26085373 Free article.

2

The importance of negative determinants as modulators of CK2 targeting. The lesson of Akt2 S131.

Vilardell J, Girardi C, Marin O, Cozza G, Pinna LA, Ruzzene M. Vilardell J, et al. Among authors: ruzzene m. PLoS One. 2018 Mar 1;13(3):e0193479. doi: 10.1371/journal.pone.0193479. eCollection 2018. PLoS One. 2018. PMID: 29494643 Free PMC article.

3

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential.

Cozza G, Girardi C, Ranchio A, Lolli G, Sarno S, Orzeszko A, Kazimierczuk Z, Battistutta R, Ruzzene M, Pinna LA. Cozza G, et al. Among authors: ruzzene m. Cell Mol Life Sci. 2014 Aug;71(16):3173-85. doi: 10.1007/s00018-013-1552-5. Epub 2014 Jan 18. Cell Mol Life Sci. 2014. PMID: 24442476 Free PMC article.

4

Exploiting the repertoire of CK2 inhibitors to target DYRK and PIM kinases.

Cozza G, Sarno S, Ruzzene M, Girardi C, Orzeszko A, Kazimierczuk Z, Zagotto G, Bonaiuto E, Di Paolo ML, Pinna LA. Cozza G, et al. Among authors: ruzzene m. Biochim Biophys Acta. 2013 Jul;1834(7):1402-9. doi: 10.1016/j.bbapap.2013.01.018. Epub 2013 Jan 27. Biochim Biophys Acta. 2013. PMID: 23360763

5

Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin.

Cozza G, Zonta F, Dalle Vedove A, Venerando A, Dall'Acqua S, Battistutta R, Ruzzene M, Lolli G. Cozza G, et al. Among authors: ruzzene m. FEBS J. 2020 May;287(9):1850-1864. doi: 10.1111/febs.15111. Epub 2019 Nov 12. FEBS J. 2020. PMID: 31661600 Free article.

6

Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2).

Cozza G, Zanin S, Determann R, Ruzzene M, Kunick C, Pinna LA. Cozza G, et al. Among authors: ruzzene m. PLoS One. 2014 Feb 24;9(2):e89176. doi: 10.1371/journal.pone.0089176. eCollection 2014. PLoS One. 2014. PMID: 24586573 Free PMC article.

7

The selectivity of inhibitors of protein kinase CK2: an update.

Pagano MA, Bain J, Kazimierczuk Z, Sarno S, Ruzzene M, Di Maira G, Elliott M, Orzeszko A, Cozza G, Meggio F, Pinna LA. Pagano MA, et al. Among authors: ruzzene m. Biochem J. 2008 Nov 1;415(3):353-65. doi: 10.1042/BJ20080309. Biochem J. 2008. PMID: 18588507

8

Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study.

Meggio F, Pagano MA, Moro S, Zagotto G, Ruzzene M, Sarno S, Cozza G, Bain J, Elliott M, Deana AD, Brunati AM, Pinna LA. Meggio F, et al. Among authors: ruzzene m. Biochemistry. 2004 Oct 12;43(40):12931-6. doi: 10.1021/bi048999g. Biochemistry. 2004. PMID: 15461466 Free article.

9

Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A.

Sarno S, Mazzorana M, Traynor R, Ruzzene M, Cozza G, Pagano MA, Meggio F, Zagotto G, Battistutta R, Pinna LA. Sarno S, et al. Among authors: ruzzene m. Cell Mol Life Sci. 2012 Feb;69(3):449-60. doi: 10.1007/s00018-011-0758-7. Epub 2011 Jul 1. Cell Mol Life Sci. 2012. PMID: 21720886 Free PMC article.

10

Design, validation and efficacy of bisubstrate inhibitors specifically affecting ecto-CK2 kinase activity.

Cozza G, Zanin S, Sarno S, Costa E, Girardi C, Ribaudo G, Salvi M, Zagotto G, Ruzzene M, Pinna LA. Cozza G, et al. Among authors: ruzzene m. Biochem J. 2015 Nov 1;471(3):415-30. doi: 10.1042/BJ20141127. Epub 2015 Sep 8. Biochem J. 2015. PMID: 26349539

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