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Probing transient non-native states in amyloid beta fiber elongation by NMR.
Brender JR , Ghosh A , Kotler SA , Krishnamoorthy J , Bera S , Morris V , Sil TB , Garai K , Reif B , Bhunia A , Ramamoorthy A . Brender JR , et al. Among authors: krishnamoorthy j. Chem Commun (Camb). 2019 Apr 11;55(31):4483-4486. doi: 10.1039/c9cc01067j. Chem Commun (Camb). 2019. PMID: 30917192 Free PMC article.
Probing the sources of the apparent irreproducibility of amyloid formation: drastic changes in kinetics and a switch in mechanism due to micellelike oligomer formation at critical concentrations of IAPP.
Brender JR, Krishnamoorthy J, Sciacca MF, Vivekanandan S, D'Urso L, Chen J, La Rosa C, Ramamoorthy A. Brender JR, et al. Among authors: krishnamoorthy j. J Phys Chem B. 2015 Feb 19;119(7):2886-96. doi: 10.1021/jp511758w. Epub 2015 Feb 3. J Phys Chem B. 2015. PMID: 25645610
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.
Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH. Lee S, et al. Among authors: krishnamoorthy j. J Am Chem Soc. 2014 Jan 8;136(1):299-310. doi: 10.1021/ja409801p. Epub 2013 Dec 27. J Am Chem Soc. 2014. PMID: 24397771 Free PMC article.
78 results